Research Article: Incidence of Systemic Vasculitis and Clinical Outcomes in Systemic Sclerosis: -Years Follow-Up of Asymptomatic Positive for Anti-Neutrophilic Cytoplasmic Antibody
Introduction:
Anti-neutrophil cytoplasmic antibodies (ANCA) are autoantibodies directed against the enzymes found within the primary granules of neutrophils and lysosomes in monocytes. These antibodies are involved in the pathogenesis of ANCA-associated vasculitis (AAV). In a retrospective study in Mexico between March and March , Martin-Nares et al reported the prevalence of overlap between AAV and systemic autoimmune disease was .%. The predominant AAV type was renal-limited vasculitis (%), followed by granulomatosis with…
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