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Research Article: A Bibliometric Analysis of Global Research Trends in Psoriasis and Metabolic Syndrome

Date Published: 2024-02-09

Abstract:
Psoriasis is an immunologically mediated refractory inflammatory skin condition with multisystemic consequences.– Recent studies strongly indicate a positive relationship between psoriasis and metabolic syndrome (MetS)., MetS is a condition characterized by enhanced inflammatory cytokine activity and a pro-inflammatory state. It is an umbrella term for a group of conditions that includes insulin resistance, obesity, type diabetes, hypertension, and dyslipidemia., Increasing observational studies have repeatedly confirmed strong associations between psoriasis and MetS and its components. The incidence of MetS among individuals afflicted with psoriasis is between % and %, with psoriasis patients having at least twice the risk of developing metabolic syndrome compared to non-psoriatic individuals. Emerging evidence indicates that psoriasis and MetS have a common genetic background, multiple metabolic risk factors, and pathogenic pathways. In the Chinese Han population, psoriasis vulgaris and MetS might share overlapping susceptible genes. The correlation between psoriasis and MetS is of significant clinical importance. Certain conventional systemic treatments should be administered with caution in psoriatic individuals with MetS due to their potential adverse effects on coexisting metabolic conditions, especially with prolonged use. As a consequence, it is essential for dermatologists to provide recommendations.

Introduction:
Psoriasis is an immunologically mediated refractory inflammatory skin condition with multisystemic consequences. – Recent studies strongly indicate a positive relationship between psoriasis and metabolic syndrome (MetS). , MetS is a condition characterized by enhanced inflammatory cytokine activity and a pro-inflammatory state. It is an umbrella term for a group of conditions that includes insulin resistance, obesity, type diabetes, hypertension, and dyslipidemia. , Increasing observational studies have repeatedly…

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