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Research Article: Non Clinical Model to Assess the Mechanism of Action of a Combined Hyaluronic Acid, Chondroitin Sulfate and Calcium Chloride: HA+CS+CaCl Solution on a D Human Reconstructed Bladder Epithelium

Date Published: 2024-01-30

Introduction:
Intravesical instillations of glycosaminoglycans (GAGs) represent a valid therapeutical approach for different pathologies, such as bladder pain syndrome/interstitial cystitis (BPS/IC), chemical induced cystitis (including BCG therapy), radiation induced cystitis (irradiation of pelvic tumors) and recurrent urinary tract infections (UTIs). In particular, UTIs are one of the most prevalent infections both in the community (only second to respiratory tract’s) and in hospital settings, affecting –% of adult women in…

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