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Research Article: Effects of Continuous Glucose Monitoring on Glycemic Control in Type 2 Diabetes: A Systematic Review and Meta-Analysis

Date Published: 2024-02-29

Abstract:
As the prevalence of diabetes is rapidly increasing, the use of continuous glucose monitoring, which is effective in improving glycemic control in type 2 diabetes, is increasing. Methods: Systematic review was performed according to PRISMA criteria. The search was conducted for articles published until 31 May 2023 in PubMed, CINAHL, Cochrane Library, EMBASE, ClinicalKey, etc. The meta-analysis involved the synthesis of effect size; tests of homogeneity and heterogeneity; trim and fill plot; Egger’s regression test; and Begg’s test for assessing publication bias. Results: 491 studies were searched, of which 17 studies that met the selection criteria were analyzed. The overall effect on HbA1c was ?0.37 (95% CI, ?0.63~?0.11, p < 0.001), with HbA1c decreasing significantly after CGM interventions. Sub-analyses showed that the study was statistically significant in those aged 60 years or older, when rt-CGM was used and when the study was performed in multiple centers. Conclusion: The results of this study showed that intervention using CGM was effective in reducing HbA1c in type 2 diabetes. The factors identified in this study can be used as guidelines for developing future CGM intervention programs.

Introduction:
Diabetes is an insidious, chronic disease, and its incidence is increasing rapidly worldwide. As indicated by the Korean Diabetes Fact Sheet, the number of diabetic patients in South Korea aged 30 or more reached around 6 million in 2020 and showed a consistent upward trend [1]. However, only 24.5% of patients had successfully managed their diabetes, as determined by the key indicator, HbA1c, which should ideally be below 6.5% [2].

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