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Research Article: Surgical Emergencies in Patients with Hemophilia A—What to Expect

Date Published: 2024-03-07

Abstract:
Surgical emergencies in patients with hemophilia A represent a major risk of mortality without proper multidisciplinary management and require prompt and effective treatment to prevent complications and improve patient outcomes. We present a short number of cases that were hospitalized in the I–II Surgery Clinic of the Emergency County Hospital “St. Spiridon” from Iasi, Romania, with hemophilia A requiring surgical emergencies. The timing of surgical intervention is very important, so the indication for surgical intervention must be made judiciously and without delay. Consequently, it is vital to ensure access to hemostatic support so surgery can be performed on these patients, ultimately saving their lives.

Introduction:
Hemophilia A and B are X-linked congenital deficiencies of factor VIII and factor IX, respectively, that occur in 0.001% of the population, with hemophilia A accounting for 85% of cases [1]. Hemophilia severity is classified based on factor activity level as mild (5–40%), moderate (1–5%), or severe (<1%). Patients with mild hemophilia often are asymptomatic and become coagulopathic only after massive trauma or major surgery. Patients with moderate or severe hemophilia may bleed spontaneously or with minor…

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