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Research Article: Low-dose-rate induces more severe cognitive impairment than high-dose-rate in rats exposed to chronic low-dose ?-radiation

Date Published: 2024-05-22

Abstract:
Background: Owing to the long penetration depth of gamma (?)-rays, individuals working in ionizing radiation environments are chronically exposed to low-dose ?-radiation, resulting in cognitive changes. Dose rate significantly affects radiation-induced biological effects; however, its role in chronic low-dose ?-irradiation-induced cognitive impairment remains unclear. We aimed to investigate whether chronic low-dose ?-irradiation at low-dose-rate (LDR) could induce cognitive impairment and to compare the cognitive alteration caused by chronic low-dose ?-irradiation at LDR and high-dose-rate (HDR).

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