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Research Article: Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis

Date Published: 2024-09-23

Abstract:
Background: Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by persistent inflammatory cascades, with macrophage activation playing a pivotal role. Chitinase 1 (CHIT1), produced by activated macrophages, is a key player in this cascade. In this study, we aimed to explore the role of CHIT1 in MASH with progressive liver fibrosis.

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