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Research Article: Correlations of the triglyceride?glucose index and modified indices with arterial stiffness in overweight or obese adults

Date Published: 2024-12-17

Abstract:
Background: Insulin resistance (IR) contributes substantially to the development of cardiovascular disease (CVD) and metabolic disorders, particularly obesity. The homeostatic model assessment of IR is a prevalent IR indicator, but insulin measurement is quite impractical for widely use. Given its convenience and accessibility, the triglyceride?glucose (TyG) index, along with modified indices such as the triglyceride?glucose?waist circumference (TyG?WC) and triglyceride?glucose?waist?height ratio (TyG?WHtR), are gaining recognition as practical tools for assessing IR. This study aimed to investigate the specific correlation between the TyG index and its modified indices with arterial stiffness in an overweight or obese population and to explore novel, self-defined modified TyG indices for identifying individuals at elevated risk for such conditions.

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