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Research Article: Understanding the link between ALDH2 genotypes and diabetes

Date Published: 2025-02-19

Abstract:
Introduction: The association between aldehyde dehydrogenase-2 (ALDH2) rs671 and diabetes remains controversial, with uncertainty about whether alcohol consumption or other factors mediate or modify this relationship. This study aimed to examine the ALDH2–diabetes association using standardized clinical criteria while systematically investigating potential confounding, mediating, and interacting factors in a community-based cohort.

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