Research Article: Is a rare CXCL8 gene variant a new possible cause or curse factor of inflammatory bowel disease?
Abstract:
Introduction: The pathogenesis of inflammatory bowel diseases (IBD) involves genetic, environmental, immunological, and microbial factors; however, it remains unclear. Pro-inflammatory interleukin 8 (IL-8), encoded by the CXCL8 gene, assumes a crucial chemotactic role in leukocyte migration.
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