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Research Article: Post-carvedilol myocardial function in cats with obstructive hypertrophic cardiomyopathy

Date Published: 2025-03-28

Abstract:
Introduction: Hypertrophic cardiomyopathy (HCM) is the most prevalent cardiac disease in cats, and one phenotype includes obstructive HCM with dynamic left ventricular outflow tract obstruction (DLVOTO). Myocardial function has been reported to be lower in cats with obstructive HCM than in non-obstructive HCM. Carvedilol, because of its pharmacological action, is expected to reduce the pressure gradient associated with DLVOTO, but no previous reports have studied its effects on myocardial function. This study aimed to evaluate myocardial function in cats with obstructive HCM with left ventricular outflow tract obstruction treated by carvedilol administration.

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