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Research Article: Development of a prediction model integrating PD-1 and ICOS for early differential diagnosis between autoimmune and viral encephalitis

Date Published: 2025-04-25

Abstract:
Background: Early diagnosis and treatment for encephalitis are crucial for improving patient outcomes and reducing the economic burden, especially given the overlapping symptoms and low specificity of auxiliary diagnostic tests between viral encephalitis (VE) and autoimmune encephalitis (AE). Since these two conditions require different treatment approaches, an early differential diagnosis between AE and VE is a critical challenge.

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