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Research Article: Analysis of the impact of rotation error on PTV margins in multiple brain metastases fractionated stereotactic radiotherapy based on single-isocenter multi-target technique

Date Published: 2025-04-25

Abstract:
Background: Rotational error cannot be overlooked in single-isocenter multi-target (SIMT) stereotactic radiotherapy. This retrospective study aimed to evaluate the treatment accuracy of linear accelerator-based fractionated stereotactic radiotherapy (FSRT) using SIMT non-coplanar volumetric modulated arc therapy (VMAT) in patients with multiple brain metastases. We explored the impact of rotational error on planning target volume (PTV) margins, providing clinical evidence for the selection of appropriate PTV margin values.

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