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Recreational MDMA use in Norway: results from an internet convenience sample

Abstract: In recent years, a renewed interest has emerged in investigating the use of MDMA in the treatment of mental disorders. However, knowledge about the characteristics of…

Date: 2025-09-26

Right atrial and right ventricular strain in patients with acute decompensated heart failure: a pilot study

Abstract: The aim of this study was to compare the right atrial (RAS: reservoir-R, conduit-CD, contraction-CT) and right ventricular strain (global longitudinal-RV-GS, free wall…

Date: 2025-09-26

Predictive models for non-response to conventional treatment in polymyositis and dermatomyositis

Abstract: Polymyositis (PM) and dermatomyositis (DM) are the major subtypes of idiopathic inflammatory myopathies with heterogeneous treatment responses. This study aimed to…

Date: 2025-09-26

HuR ablation destabilizes Foxp3 mRNA and impairs regulatory T cell function, contributing to an autoimmune phenotype

Abstract: The RNA-binding protein HuR (Elavl1), a key post-transcriptional regulator, plays a critical role in T cell activation and function by stabilizing target mRNAs. To…

Date: 2025-09-26

Scientific and regulatory progress in advancing paediatric oncology drug development in the EU and in the US

Abstract: This study provides an updated overview of progress in paediatric oncology, following legislative and regulatory initiatives in the European Union (EU) and in the United…

Date: 2025-09-26

Dendrobium huoshanense C. Z. Tang & S. J. Cheng alleviates atherosclerosis by reducing lipid and improving vascular endothelial dysfunction

Abstract: Dendrobium huoshanense C. Z. Tang & S. J. Cheng (DH) water extract has previously been found to have therapeutic effects on atherosclerosis (AS), but the active…

Date: 2025-09-26

Isolation and genomic analysis of phage BUCT551 against drug-resistant Aeromonas hydrophila

Abstract: Aeromonas hydrophila ( A. hydrophila ) is a common pathogen in aquaculture that also causes opportunistic infections and sporadic food- and water-borne illness in…

Date: 2025-09-26

Exploring behavioral factors and emotional mechanisms underlying older adult users' adoption of smart health services: evidence from PLS-SEM and fsQCA

Abstract: In a population aging society, home-based older adult care as the primary model have experienced a robust growth in demand for smart health services (SHS), reflecting an…

Date: 2025-09-26

Knowledge, attitude, and quality of life among newly diagnosed type 2 diabetic patients attending diabetic clinics at Bugando Medical Centre, Mwanza, Tanzania

Abstract: Diabetes mellitus, particularly type 2 diabetes, is a rapidly escalating global health issue. The World Health Organization projects a significant increase in diabetes…

Date: 2025-09-26

Internalized stigma and caregiver burden among caregivers of adolescents with non-suicidal self-injury: a moderated mediation analysis

Abstract: Adolescent non-suicidal self-injury (NSSI) constitutes a critical global health challenge, generating profound internalized stigma and familial burden among caregivers.…

Date: 2025-09-26