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From promise to practice: insights into ChatGPT-4o use in child and adolescent mental health from professionals

Abstract: Despite growing interest, empirical studies on ChatGPT-4o’s clinical role in child and adolescent mental health remain scarce. This study explored child and adolescent…

Date: 2025-09-26

Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy

Abstract: Chondrosarcoma, a malignant bone tumor, exhibits a high incidence rate. This study employed network pharmacology and cell-based experiments to explore the molecular…

Date: 2025-09-26

Integrated 3D printing and case-based learning in orthopedic residency education for geriatric hip fracture management

Abstract: Geriatric hip fractures, clinically designated as “the last fracture in life” due to significant disability and mortality, pose critical educational barriers for…

Date: 2025-09-26

Comparative analysis of hemostatic efficacy and safety: absorbable gelatin sponge with hemostatic fluid gelatin vs. tranexamic acid in posterior cervical expansive open-door laminoplasty

Abstract: Posterior cervical expansive open-door laminoplasty carries significant intraoperative bleeding risks from Batson's plexus. While hemostatic agents such as absorbable…

Date: 2025-09-26

The dual association of serum uric acid with the functional outcomes of patients after hip arthroplasty: 1-year follow-up study

Abstract: Serum uric acid (UA) exhibits dual biological roles as both an antioxidant and a pro-oxidant, yet its impact on functional recovery after hip arthroplasty remains…

Date: 2025-09-26

Explainable machine learning model for predicting the outcome of acute ischemic stroke after intravenous thrombolysis

Abstract: Acute ischemic stroke (AIS) patients often experience poor functional outcomes post-intravenous thrombolysis (IVT). Novel computational methods leveraging machine…

Date: 2025-09-26

Predicting radiation pneumonitis with dose-segmented radiomics in locally advanced non- small cell lung cancer patients undergoing consolidative immunotherapy post- concurrent chemoradiotherapy

Abstract: To develop and validate a machine learning model that integrates dose distribution-based radiomics, clinicopathological parameters, and hematological inflammatory…

Date: 2025-09-26

Digital support and artificial intelligence in cancer patients undergoing radiation therapy: patient utilization, acceptance and attitudes

Abstract: New technologies, such as digital support tools or artificial intelligence (AI) in cancer diagnostics and treatment, offer new possibilities for cancer care. Evidence on…

Date: 2025-09-26

Efficacy and safety of antiangiogenic agents combined with HIFU in the treatment of advanced liver cancer

Abstract: Although antiangiogenic agents and HIFU (High-intensity focused ultrasound) are extensively used in the systematic treatment of advanced primary and secondary liver…

Date: 2025-09-26

Somatic mutations in angiogenesis-related pathways and RNA polymerase II activity in sporadic brain arteriovenous malformations

Abstract: Sporadic brain arteriovenous malformations (bAVMs) are rare vascular anomalies characterized by abnormal angiogenesis and direct arteriovenous shunting. While the VEGF…

Date: 2025-09-26