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Randomised, open-label, non-inferiority clinical trial on the efficacy and safety of a 7-day vs 14-day course of antibiotic treatment for uncomplicated enterococcal bacteraemia: the INTENSE trial protocol

Abstract: Introduction Enterococcus spp is responsible for 8%–15% of total bacteraemias with an associated global mortality around 23%–30%. Regarding the clinical management of…

Date: 2023-09-06

Study protocol for IMPRoVE: a multicentre prospective observational cohort study of the incidence, impact and mechanisms of perioperative right ventricular dysfunction in non-cardiac surgery

Abstract: Introduction Perioperative myocardial injury evidenced by elevated cardiac biomarkers (both natriuretic peptides and troponin) is common after major non-cardiac surgery.…

Date: 2023-09-06

Exploring barriers and facilitators of primary care physicians towards optimising statin therapy in patients with hyperlipidaemia in the very high-risk group: a qualitative study in Singapore

Abstract: Objectives To explore the perspectives of primary care physicians with regard to the barriers and facilitators towards optimising statin therapy in patients with…

Date: 2023-09-06

Health systems efficiency in China and ASEAN, 2015–2020: a DEA-Tobit and SFA analysis application

Abstract: Objective To evaluate the health systems efficiency in China and Association of Southeast Asian Nations (ASEAN) countries from 2015 to 2020. Design Health efficiency…

Date: 2023-09-06

Where do those experiencing sexual violence seek help and is routine enquiry acceptable within a sexual healthcare setting? Findings from a population-based survey

Abstract: Objectives Most sexual violence (SV) remains undisclosed to healthcare professionals. The aims of this study were to identify where support would be sought after SV and…

Date: 2023-09-06

Cost–utility analysis of commonly used anti-glaucoma interventions for mild-to-moderate primary open-angle glaucoma patients in rural and urban China

Abstract: Objective An increasing number of studies have explored the clinical effects of antiglaucoma surgical procedures; however, economic evidence was scarce. We aimed to…

Date: 2023-09-06

Sequential multiple assignment randomised controlled trial protocol for developing an adaptive intervention to improve depressive symptoms among family caregivers of people with dementia

Abstract: Objectives Family caregivers of people with dementia (FC-of-PWD) suffer from a high level of stress and depressive symptoms, which usually require different…

Date: 2023-09-06

Modelling NHS England 111 demand for primary care services: a discrete event simulation

Abstract: Objectives This feasibility study aimed to model in silico the current healthcare system for patients triaged to a primary care disposition following a call to National…

Date: 2023-09-06

Safety of influenza vaccination during pregnancy: a systematic review

Abstract: Objective We conducted a systematic review to evaluate associations between influenza vaccination during pregnancy and adverse birth outcomes and maternal non-obstetric…

Date: 2023-09-06

Undernutrition in children aged 0–59 months by region and over time: secondary analysis of the Burkina Faso 2012–2018 National Nutrition Surveys

Abstract: The global burden of undernutrition remains high, responsible for significant under-five mortality in resource-limited settings. Numerous sustainable development goals…

Date: 2023-09-06