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Determination and clinical features of bone pseudoprogression in metastatic breast cancer

Abstract: Bone is one of the most common sites of metastasis for breast cancer. The classification of new osteoblastic lesions as progressive disease is currently controversial.…

Date: 2025-09-25

Relationship between nontraditional lipid parameters and the risk of type 2 diabetes in individuals recovered from dyslipidemia: a cohort study

Abstract: Lipid profiles are essential for assessing type 2 diabetes (T2D) risk, but individuals who recover from dyslipidemia are often overlooked, leaving their residual risk…

Date: 2025-09-25

Elevated novel inflammatory markers in heart failure patients are associated with increased risk of adverse outcomes within one year: insights from a longitudinal study

Abstract: Inflammation has been widely recognized as a key contributor to the pathogenesis of numerous diseases, including cardiovascular disorders. This study aims to investigate…

Date: 2025-09-25

Association between cardiopulmonary exercise capacity and clinical parameters in post-PCI patients with coronary artery disease from Fujian, China

Abstract: Peak oxygen uptake (VO?peak) assessed by cardiopulmonary exercise testing (CPET) is a key indicator of functional capacity and prognosis in patients with coronary artery…

Date: 2025-09-25

The independent value and clinical significance of angio-based microvascular resistance in predicting adverse cardiovascular events in patients with acute ST-elevation myocardial infarction

Abstract: Angio-based microvascular resistance (AMR) may influence the incidence of major adverse cardiovascular events (MACE) in patients with ST-segment elevation myocardial…

Date: 2025-09-25

Uncovering subclinical cardiotoxicity across chemotherapy phases in pediatric oncology

Abstract: Advances in cancer therapies have significantly improved survival rates in children. However, treatment-related toxicities remain common. This study aims to evaluate the…

Date: 2025-09-25

Predictive value of the quantitative flow ratio after pretreatment and drug-coated balloon therapy for functional stenosis of target vessels at the mid-term follow-up

Abstract: Drug-coated balloon (DCB) treatment requires adequate preconditioning of target lesions. The quantitative flow ratio (QFR) is an emerging method for assessing functional…

Date: 2025-09-25

VFM-SSL-BMADCC-Framework: vision foundation model and self-supervised learning based automated framework for differential cell counts on whole-slide bone marrow aspirate smears

Abstract: Differential cell counts (DCCs) on bone marrow aspirate (BMA) smear is a critical step in the diagnosis and treatment of blood and bone marrow diseases. However, manual…

Date: 2025-09-24

Prognostic value of the CIPA nutritional screening tool in over 30,000 hospitalized patients: a retrospective study (2014–2022)

Abstract: Malnutrition is a well-established negative prognostic factor in hospitalized patients, contributing to increased morbidity and mortality. The CIPA (Control of Food…

Date: 2025-09-24

Epidemiologic characteristics of leprosy in Mainland China, 2004–2020

Abstract: Leprosy is a chronic infectious disease caused by Mycobacterium leprae . This study aimed to elucidate the epidemiological characteristics of this condition in China…

Date: 2025-09-24