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The significance of biological samples from pregnant women in cervical intraepithelial neoplasia

Abstract: Cervical cancer remains a significant threat to women’s health, with pregnant women representing a particularly vulnerable population. This study aimed to investigate…

Date: 2025-09-16

Effectiveness and safety of ciprofol for the induction and maintenance of general anesthesia in urological surgery: a prospective, non-inferiority cohort study

Abstract: Ciprofol is a newly developed intravenous agent, with limited clinical data available to date. The study aimed to evaluate the effectiveness and safety of ciprofol for…

Date: 2025-09-16

Associations between suicide attempts and clinical, metabolic, and inflammatory markers in Chinese patients with long-term schizophrenia

Abstract: Suicide attempt (SA) is common among patients with long-term schizophrenia (SCZ), but the mechanisms underlying its occurrence remain incompletely understood. Thus, the…

Date: 2025-09-16

Symptom-level interactions between anxiety and internet addiction in Chinese adolescents: a large-scale network and residence difference analysis

Abstract: Anxiety and Internet addiction (IA) are prevalent and exhibit a strong correlation among adolescents. This study aimed to (a) identify key symptoms and relationships of…

Date: 2025-09-16

Network characteristics of emotional resilience, anxiety, and depression among Chinese adolescents and their gender differences

Abstract: To explore the network structure of emotional resilience and anxiety-depressive symptoms in adolescents and identify gender differences in these networks. A convenience…

Date: 2025-09-16

Burden of osteoarthritis in older adults (aged ?55?years) in the United States and China: a comparative analysis of temporal trends, risk factor contributions, and projected burden to 2030 using global burden of disease study 2021 data

Abstract: Osteoarthritis (OA) is a leading cause of disability worldwide, with aging populations and rising obesity rates being notable contributing factors. This study examines…

Date: 2025-09-16

The predictive role of platelet-to-lymphocyte ratio and systemic immune-inflammation index in young and middle-aged patients with tibial plateau fractures

Abstract: There is suggestive evidence that the platelet-to-lymphocyte ratio (PLR) and systemic immune-inflammation index (SII) are related to the severity of fracture. The…

Date: 2025-09-16

Association of inflammation and nutrition-based indicators and diabetic foot ulcers: a cross-sectional study and a retrospective study

Abstract: Inflammation and nutrition status have emerged as important factors in impaired wound healing in diabetes. However, the association between inflammation and…

Date: 2025-09-16

Identification of amino acid metabolism-related gene Leucyl-tRNA synthetase 1 (LARS1) as a potential prognostic and therapeutic target in hepatocellular carcinoma

Abstract: Amino acid metabolism plays a critical role in tumorigenesis in hepatocellular carcinoma (HCC). Thus, we explore the amino acid metabolic profile in HCC to construct…

Date: 2025-09-16

Platelet-to-high-density lipoprotein cholesterol ratio as a predictor of stroke risk: a longitudinal analysis of the China health and retirement longitudinal study

Abstract: Stroke is a major health concern in aging populations. This study investigates the platelet-to-high-density lipoprotein cholesterol ratio (PHR) as a predictor of stroke…

Date: 2025-09-16