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Comparative single-cell immune responses in peripheral blood and lymph node of immunized SARS-CoV-2 challenged infant rhesus macaques

Abstract: A better understanding of post-exposure immune responses in vaccinated individuals, particularly infants, is needed. Using a rhesus macaque model, we compared recipients…

Date: 2025-09-15

First report from the Czech national registry of inborn errors of immunity (2012–2025)

Abstract: Congenital immune system defects represent an ever-growing group of diseases characterized by increased susceptibility to infections and association with autoimmune,…

Date: 2025-09-15

Morphological and quantitative CT features of anterior mediastinal lesions in TAFRO syndrome and idiopathic multicentric Castleman disease

Abstract: We investigated the diagnostic challenges of TAFRO syndrome and idiopathic multicentric Castleman disease (iMCD), focusing on the usefulness of anterior mediastinal…

Date: 2025-09-15

Long-term follow-up of patients with relapsed/refractory multiple myeloma after BCMA CAR-T-cell therapy

Abstract: B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T-cell therapy has demonstrated potent short-term efficacy in patients with relapsed/refractory…

Date: 2025-09-12

Age-enhanced MAGIC algorithm predicts mortality in pediatric aGVHD: a multicenter study

Abstract: Acute graft-versus-host disease (aGVHD) is a major contributor to non-relapse mortality (NRM) in pediatric patients undergoing allogeneic hematopoietic stem cell…

Date: 2025-09-12

Comparative models on low multiplier DRG classification for advanced lung cancer

Abstract: This study aimed to compare the performance of machine learning models in predicting low multiplier DRGs for advanced lung cancer, and to identify the optimal algorithm…

Date: 2025-09-12

Investigation of validity evidence for the Coach Precompetitive Communication Questionnaire-Preference for measurement of collegiate athlete preferences of coach speech content and delivery

Abstract: Previous measures of athlete perception of pregame speech have centered around a two-dimensional structure of speech content (i.e., tactical and emotional), although…

Date: 2025-09-12

A real-time imaging approach to quantify dendritic cell internalization for immunogenicity risk assessment of biotherapeutics

Abstract: The presence of treatment-emergent anti-drug antibodies (ADAs) can pose challenges during biotherapeutic development by compromising drug safety and efficacy. Early…

Date: 2025-09-12

Determinants of the lost to follow-up status among patients with tuberculosis who emigrated to the Republic of Korea: a mixed-method study

Abstract: Tuberculosis (TB) remains a significant global health concern, with foreign migrants in the Republic of Korea (ROK) representing a particularly vulnerable group; despite…

Date: 2025-09-12

Untargeted metabolomic profiling in acute ischemic stroke patients with cerebral microbleeds

Abstract: Acute ischemic stroke (AIS) is a common cerebrovascular condition. Cerebral microbleeds (CMBs) are frequently observed in AIS patients and are closely associated with…

Date: 2025-09-12