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Identification of palliative care needs and prognostic factors of survival in tailoring appropriate interventions in advanced oncological, renal and pulmonary diseases: a prospective observational protocol

Abstract: Introduction It is estimated that of those who die in high-income countries, 69%–82% would benefit from palliative care with a high prevalence of advanced chronic…

Date: 2023-05-30

Neoadjuvant camrelizumab plus chemotherapy for locally advanced cervical cancer (NACI Study): a study protocol of a prospective, single-arm, phase II trial

Abstract: Introduction Neoadjuvant chemotherapy (NACT) is an emerging approach for locally advanced cervical cancer (LACC). However, the clinical response and postoperative…

Date: 2023-05-30

Immunogenicity and safety of mixed COVID-19 vaccine regimens in patients with immune-mediated inflammatory diseases: a single-centre prospective cohort study

Abstract: Objective Among persons with immune-mediated inflammatory diseases (IMIDs) who received SARS - CoV-2 vaccines, we compared postvaccine antibody responses and IMID…

Date: 2023-05-30

Telehealth-delivered naturalistic developmental behavioural intervention with and without caregiver acceptance and commitment therapy for autistic children and their caregivers: protocol for a multi-arm parallel group randomised clinical trial

Abstract: Introduction Timely access to early support that optimises autistic children’s development and their caregiver’s mental health is critical. Naturalistic developmental…

Date: 2023-05-30

Identify and classify interprofessional primary care performance indicators: a scoping review protocol

Abstract: Introduction Measuring the performance of interprofessional primary care is needed to examine whether this model of care is achieving its desired outcomes on patient…

Date: 2023-05-30

Dynamic treatment regimes (DTRs) to study treatment sequencing in oncology: a scoping review protocol

Abstract: Introduction The rapid evolution of the therapeutic landscape in oncology poses challenges to optimal treatment sequencing. Evidence for clinical decision-making is…

Date: 2023-05-30

Choice of anaesthesia in microelectrode recording-guided deep-brain stimulation for Parkinson’s disease (CHAMPION): study protocol for a single-centre, open-label, non-inferiority randomised controlled trial

Abstract: Introduction Deep brain stimulation (DBS) implantation under general anaesthesia (GA) has been applied to patients with Parkinson’s disease (PD) with severe…

Date: 2023-05-30

Mapping health service coverage inequalities in Africa: a scoping review protocol

Abstract: Introduction Addressing inequities in health service coverage is a global priority, especially with the resurgence of interest in universal health coverage. However, in…

Date: 2023-05-30

Adverse drug reactions of non-statin antihyperlipidaemic drugs in China from 1989 to 2019: a national database analysis

Abstract: Objective This study aims to understand the adverse drug reactions (ADRs) for non-statin antihyperlipidaemic drugs included in the China Anti-hyperlipidemic Drug…

Date: 2023-05-30

Psychometric properties of Hamilton Depression Rating Scale among people with epilepsy in Jimma University Medical Center, Neurology Clinic, Southwest Ethiopia, 2020: cross-sectional study.

Abstract: Objective It is crucial to use clinically validated instruments to detect and treat depression in people with epilepsy. Therefore, this study aimed to describe the…

Date: 2023-05-30