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Decoding neutrophil extracellular traps and key gene drivers in unexplained pregnancy loss

Abstract: Recurrent pregnancy loss (RPL) represents a critical reproductive health concern, with nearly half of RPL cases lacking clinically identifiable etiologies, termed…

Date: 2025-09-08

Prognostic model of ubiquitination-related genes in ovarian cancer based on transcriptomic analysis and experimental validation

Abstract: Ubiquitination plays a crucial role in the malignant progression of ovarian cancer. With the advent of proteolysis-targeting chimeras (PROTACs) targeting ubiquitin…

Date: 2025-09-08

The differential impacts of environmental air pollution exposure on the risk of placenta previa and placenta accreta in twin pregnancies

Abstract: This study aims to investigate the association between exposure to air pollutants during pregnancy (until placental accreta) in twin pregnancies and the risk of abnormal…

Date: 2025-09-08

Learning curve of ultrasound-guided caudal epidural block: a CUSUM pivotal analysis

Abstract: This study aims to dynamically evaluate the learning curve of anesthesiology residents’ mastery of ultrasound-guided caudal epidural block (US-CEB) through cumulative…

Date: 2025-09-08

Impact and predictive modeling of risk factors for involuntary psychiatric admissions before and during COVID-19: insights from a Romanian tertiary hospital

Abstract: The COVID-19 pandemic significantly reshaped involuntary psychiatric hospitalizations, disrupting the balance between patient rights, public safety, and healthcare…

Date: 2025-09-08

Deep phenotyping of eyes shut homolog-associated retinopathy based on visual impairment patterns

Abstract: This study aimed to classify the phenotypes of eyes shut homolog ( EYS )-associated retinopathy based on visual impairment patterns and investigate their…

Date: 2025-09-08

Global burden and projections of stroke and its subtypes attributable to high alcohol use during 1990–2021: insights from the global burden of disease study 2021

Abstract: Stroke represents a critical public health challenge with far-reaching global implications for human health. In this study, we seek to characterize the global trends in…

Date: 2025-09-08

An ingenious 3D-printed navigating template for accurate screw placement in lumbar spinal stenosis

Abstract: To investigate the feasibility, accuracy, and safety of using a 3D-printed navigating template in transforaminal lumbar intervertebral fusion (TLIF) for treating lumbar…

Date: 2025-09-08

The burden of motor neuron diseases in Asia, 1990–2021: temporal patterns and age-period-cohort analyses

Abstract: This study aims to characterize the temporal trends of motor neuron diseases (MNDs) burden in Asia from 1990 to 2021, estimate their age, period and cohort effects, and…

Date: 2025-09-08

Diabetic Striate Syndrome: an uncommon complication of diabetes requiring further conceptual expansion

Abstract: Diabetic Striate Syndrome (DSS) is a rare complication of diabetes, clinically characterized by chorea-like involuntary movements and contralateral basal ganglia…

Date: 2025-09-08