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Association of life's essential 8 and genetic predisposition with the risk of osteoarthritis: a prospective cohort study

Abstract: Osteoarthritis (OA) is a prevalent joint disorder with significant health and economic impacts. While individual cardiovascular health (CVH) factors have been linked to…

Date: 2025-09-05

Videos in short-video sharing platforms as sources of information on osteoarthritis: cross-sectional content analysis study

Abstract: Osteoarthritis (OA) is a debilitating condition characterized by pain, stiffness, and impaired mobility, significantly affecting patients' quality of life. Health…

Date: 2025-09-05

Simultaneous profiling of the blood and gut T and B cell repertoires in Crohn’s disease and symptomatic controls illustrates tissue-specific alterations in the immune repertoire of individuals with Crohn’s disease

Abstract: Crohn’s disease (CD) is a clinical subset of inflammatory bowel disease that is characterized by patchy transmural inflammation across the gastrointestinal tract.…

Date: 2025-09-05

Transforming Alzheimer’s disease nursing: integrating holistic care, innovative interventions, and evidence-based practices for enhanced patient outcomes

Abstract: Alzheimer’s disease (AD) represents a significant global healthcare challenge with increasing prevalence in aging populations. Traditional care models often focus…

Date: 2025-09-05

Mechanical thrombectomy for mild stroke with anterior circulation large vessel occlusion: a multicenter cohort study

Abstract: The clinical benefit of mechanical thrombectomy (MT) for anterior circulation emergency large vessel occlusion (ELVO) in patients presenting with a mild National…

Date: 2025-09-05

Mesenchymal stem cells enhanced with SeNPs protection against CLP induction associated with liver injury are mediated via antioxidant, anti-inflammatory, and immunomodulatory activities

Abstract: Sepsis-induced liver injury is a serious issue in critical care. Since antibiotics are insufficiently effective to combat the disease and avoid upcoming organ failure,…

Date: 2025-09-05

Inhibition of IL-27 signaling regulates chemokine levels and sustains CXCR2 receptor expression on mononuclear cells to improve disease outcomes during gram-negative neonatal sepsis

Abstract: Interleukin-27 (IL-27) is a cytokine that belongs to the IL-6/IL-12 cytokine family with diverse influences on the immune response. Elevated levels of IL-27 cytokine…

Date: 2025-09-05

Evaluating the association between gestational diabetes and neonatal hypoglycemia in Taiwan: a retrospective study of 2,149 pregnancies

Abstract: To determine whether gestational diabetes mellitus (GDM) is associated with an increased risk of neonatal hypoglycemia and adverse neonatal outcomes in a Taiwanese…

Date: 2025-09-04

The role of LSR gene variants in early onset intrahepatic cholestasis: a case series with treatment options

Abstract: We report on three children with novel variants in the lipolysis-stimulated lipoprotein receptor ( LSR ) gene with clinical presentation with early onset intrahepatic…

Date: 2025-09-04

Perceptions and moral distress in surplus embryo disposition among Japanese IVF patients: a qualitative study

Abstract: The growing use of in vitro fertilization (IVF) in Japan has led to an increase in surplus frozen embryos and the associated ethical dilemmas. Cultural values,…

Date: 2025-09-04