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Risk factors for emergency cesarean delivery in patients with placenta accreta spectrum: a multicenter retrospective cohort study

Abstract: Pregnant women with placenta accreta spectrum (PAS), particularly those with placenta increta or placenta percreta, undergoing emergency cesarean section are at a high…

Date: 2025-09-03

NADH supplementation improves human oocyte maturation and developmental competence of resulting embryos in controlled ovarian hyperstimulation cycles: a pilot study implicating the CDK2/GAS6 signaling pathway

Abstract: Mitochondrial dysfunction in immature oocytes remains a critical barrier to successful in vitro maturation (IVM), particularly in cases of diminished ovarian reserve.…

Date: 2025-09-03

Systemic immune inflammatory index and mortality in chronic kidney disease

Abstract: Chronic kidney disease (CKD) is common and linked to higher mortality rates, but its relationship with the systemic immunoinflammatory index (SII) remains unclear,…

Date: 2025-09-03

Prevalence of antenatal depression and its association with adverse childhood experiences: a cross- sectional study at Hospital Canselor Tuanku Muhriz, Kuala Lumpur

Abstract: Emerging evidence suggests a link between adverse childhood experiences (ACEs) and antenatal depression, with a higher number of maternal ACEs associated with increased…

Date: 2025-09-03

Inhibitory and excitatory conditioned cues associated with alcohol differentially modulate the nucleus accumbens shell: involvement of 5-HT 7 receptors

Abstract: The ability of conditioned cues to evoke drug craving is considered a critical factor precipitating relapse of drug use. The nucleus accumbens shell (AcbSh) is a…

Date: 2025-09-03

Predictors of response to anti-VEGF combined with laser therapy in severe non-proliferative diabetic retinopathy: development and validation of a nomogram model from retrospective data

Abstract: Anti-vascular endothelial growth factor (anti-VEGF) and laser combination therapy demonstrates variable efficacy in severe non-proliferative diabetic retinopathy, with…

Date: 2025-09-03

Diagnostic lncRNA biomarkers and immune-related ceRNA networks for osteonecrosis of the femoral head in metabolic syndrome identified by plasma RNA sequencing and machine learning

Abstract: Osteonecrosis of the femoral head (ONFH) is a disabling orthopedic condition that remains challenging to diagnose at an early stage. Recent evidence suggests that immune…

Date: 2025-09-03

Application of anterior minimally invasive clamping technique combined with lower extremity axial bone traction device in irreducible intertrochanteric fractures

Abstract: This study aims to evaluate the effectiveness of the anterior minimally invasive clamping technique in conjunction with a lower extremity axial bone traction device for…

Date: 2025-09-03

Short-term air pollution and fracture admissions in Beijing

Abstract: Limited evidence exists on the links between ambient air pollution and fractures. This study aimed to investigate the association between short-term exposure to criteria…

Date: 2025-09-03

Association between blood cobalt ion concentrations and anemia and cardiovascular diseases: novel evidence of toxicity resulting from metal implants

Abstract: Cobalt ions released from metal objects pose potential systemic toxicity risks, yet comprehensive epidemiological evidence linking blood cobalt ion concentrations with…

Date: 2025-09-03