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A modified swan incision combined with lateral rectus suspension for exotropia: a retrospective cohort study demonstrating shorter operative time and faster recovery

Abstract: A modified Swan incision (MSI) combined with lateral rectus muscle suspension surgery represents an innovative strabismus surgical technique developed by our research…

Date: 2025-09-19

Cytokine profiles in the aqueous humor of uveal melanoma: implications for tumor progression and radiation response

Abstract: This study aimed to investigate the cytokine profile in the aqueous humor of uveal melanoma (UM) and explore the role of cytokines in tumor progression and radiation…

Date: 2025-09-19

A modified surgical technique for children recurrent popliteal cyst: the repair method of using medial head of gastrocnemius tendon flap

Abstract: To investigate the efficacy of gastrocnemius medial head tendon flap repair in the treatment of recurrent popliteal cysts in children. A retrospective analysis was…

Date: 2025-09-19

Identification and analysis of diverse cell death patterns in osteomyelitis via microarray-based transcriptome profiling and clinical data

Abstract: Osteomyelitis (OM) is a debilitating infectious disease characterized by inflammation of the bone and bone marrow. Emerging evidence suggests that multiple forms of…

Date: 2025-09-19

A two-transcript classifier model of host genes for discrimination of bacterial from viral infection in ulcerative colitis with opportunistic infections: a discovery and validation study

Abstract: We aimed to develop and validate a classifier model to discriminate bacterial from viral infection in ulcerative colitis with opportunistic infections (UC-OI) by…

Date: 2025-09-19

The association between bone turnover biomarkers and the severity of white matter hyperintensities

Abstract: Bone health may be associated with cerebral small vessel disease. This study aims to explore the correlation between bone turnover biomarkers (BTMs) and parathyroid…

Date: 2025-09-19

Thrombus migration in intracranial large vessel occlusion: course, predictors, and impact on endovascular thrombectomy

Abstract: Thrombus migration (TM) is occasionally observed in patients with acute ischemic stroke undergoing endovascular thrombectomy (EVT) for large vessel occlusion. However,…

Date: 2025-09-19

Heterologous prime-pull mucosal vaccination with an adjuvanted RBD vaccine elicits robust IgA production and protects against SARS-CoV-2

Abstract: Despite the efficacy of approved severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in preventing severe disease and death, breakthrough infections…

Date: 2025-09-19

Opto-CD28-REACT: optogenetic co-stimulatory receptor activation on non-engineered human T cells

Abstract: T-cell activation is a highly regulated process requiring both antigen recognition via the T-cell receptor (TCR) and co-stimulatory signaling, notably through the…

Date: 2025-09-19

Blinatumomab demonstrates MRD eradication in MRD-positive/chemotherapy-delayed pediatric B-ALL and high response in relapsed/refractory cases: a multicenter cohort study

Abstract: Blinatumomab, a bispecific T-cell engager targeting CD3+ and CD19+, promotes T cell–mediated cytotoxicity against B-cell precursor acute lymphoblastic leukemia (B-ALL).…

Date: 2025-09-18