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Predictive factors for HbA1c and weight loss associated with semaglutide treatment in type 2 diabetes mellitus: real-world clinical evidence

Abstract: This study aimed to identify clinical predictors associated with reductions in HbA1c and weight among patients with type 2 diabetes mellitus (T2DM) treated with…

Date: 2025-09-16

Relationships among the triglyceride-glucose index, its changes, and the development of metabolically obese normal weight are strengthened by increased visceral fat area

Abstract: Metabolically obese normal weight (MONW), obesity with a normal body mass index, is often neglected due to the seemingly normal weight but has a high risk of metabolic…

Date: 2025-09-16

Th17-associated cytokine gene hypomethylation reflects epigenetic dysregulation in graves’ disease

Abstract: Graves’ disease (GD) is an organ-specific autoimmune disorder characterized by the presence of thyroid-stimulating hormone receptor autoantibodies (TRAb), leading to…

Date: 2025-09-16

Current status of national regulations on tanning bed use and workers' protection from solar ultraviolet radiation: results from a global International League of Dermatological Societies (ILDS) questionnaire study

Abstract: Exposure to ultraviolet radiation (UVR) is the most important risk factor for the development of skin cancer. Outdoor workers and people who use tanning beds belong to…

Date: 2025-09-16

Safety and efficacy of ultrasound-guided distal forearm median nerve block for pediatric trigger thumb release: a retrospective observational study in a southern Chinese cohort

Abstract: The aim of this study was to evaluate the clinical outcomes of ultrasound-guided distal forearm median nerve block (UDFMNB) in children undergoing A1 pulley release. We…

Date: 2025-09-16

Development of a nomogram for predicting postoperative Hirschsprung-associated enterocolitis

Abstract: To analyze the risk factors for postoperative Hirschsprung-associated enterocolitis (HAEC) and establish a nomogram to predict the incidence of HAEC. All patients with…

Date: 2025-09-16

The relationship between genotype and phenotype in Chinese children with glucose transporter type 1 deficiency syndrome

Abstract: Glucose transporter type 1 deficiency syndrome (Glut1DS) is a treatable neurogenetic metabolic disorder caused by pathogenic variants in the SLC2A1 gene. The…

Date: 2025-09-16

Exploring the mediating factors linking adverse childhood experiences to traditional Chinese quality of life among older adults: a multi-factorial analysis

Abstract: The global population is aging rapidly, making the facilitation of positive aging a pivotal issue that necessitates immediate global attention. This study investigates…

Date: 2025-09-16

Surgical outcomes of the closure of mesenteric defects in side-to-side jejunoileal anastomosis plus proximal loop ligation (SSJIBL) using absorbable and non-absorbable surgical sutures

Abstract: Mesenteric hiatal hernia represents a significant complication following gastrointestinal surgery, and the closure of mesenteric defects has been shown to mitigate the…

Date: 2025-09-16

A taste of one’s own medicine: Bacillus velezensis isolated from adult housefly intestines demonstrates effective fly control

Abstract: Bacillus spp. are widely used as biological agents for managing diseases in crops, livestock, poultry, and aquatic animals. Bacillus velezensis , a novel species within…

Date: 2025-09-16