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Global trends in low back pain and neck pain in the working population: implications for occupational health

Abstract: This study systematically evaluated the global burden of low back pain (LBP) and neck pain (NP) among individuals aged 20–65 from 1990 to 2021, utilizing data from the…

Date: 2025-09-15

Repeated thyroid function evaluations in the dog: a retrospective study of 8,309 dogs

Abstract: Hypothyroidism in dogs is a common diagnosis with some breeds being more prone to the condition. Autoimmune thyroiditis has an inherited component. Breeders wish to…

Date: 2025-09-15

Analysis of self-transcendence status and influencing factors in gastric cancer patients undergoing chemotherapy: a random forest model-based study

Abstract: To investigate the current status and determinants of self-transcendence in gastric cancer patients undergoing chemotherapy and to establish a foundation for clinical…

Date: 2025-09-15

A comparison of trends in the incidence of non-alcoholic steatohepatitis-related liver cancer in the BRICS countries from 1990 to 2021, alongside projections for the next 15 years

Abstract: Despite the ongoing rise in the global burden of non-alcoholic steatohepatitis-related liver cancer (NALC), systematic analyses and long-term trend projections of the…

Date: 2025-09-15

Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and the risk of early-onset post-stroke depression: a prospective study

Abstract: The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is a recently emerging composite biomarker of atherogenic lipid…

Date: 2025-09-15

Comparative single-cell immune responses in peripheral blood and lymph node of immunized SARS-CoV-2 challenged infant rhesus macaques

Abstract: A better understanding of post-exposure immune responses in vaccinated individuals, particularly infants, is needed. Using a rhesus macaque model, we compared recipients…

Date: 2025-09-15

First report from the Czech national registry of inborn errors of immunity (2012–2025)

Abstract: Congenital immune system defects represent an ever-growing group of diseases characterized by increased susceptibility to infections and association with autoimmune,…

Date: 2025-09-15

Morphological and quantitative CT features of anterior mediastinal lesions in TAFRO syndrome and idiopathic multicentric Castleman disease

Abstract: We investigated the diagnostic challenges of TAFRO syndrome and idiopathic multicentric Castleman disease (iMCD), focusing on the usefulness of anterior mediastinal…

Date: 2025-09-15

Long-term follow-up of patients with relapsed/refractory multiple myeloma after BCMA CAR-T-cell therapy

Abstract: B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T-cell therapy has demonstrated potent short-term efficacy in patients with relapsed/refractory…

Date: 2025-09-12

Age-enhanced MAGIC algorithm predicts mortality in pediatric aGVHD: a multicenter study

Abstract: Acute graft-versus-host disease (aGVHD) is a major contributor to non-relapse mortality (NRM) in pediatric patients undergoing allogeneic hematopoietic stem cell…

Date: 2025-09-12