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Manganese deficiency or dietary manganese(III) oxide nanoparticle supplementation: consequences for hematology, and intestinal and brain immunity in rats

Abstract: Introduction: The study aimed to determine the effect of manganese (Mn) exclusion from the mineral mixture added to the rat diet and replacing the recommended level of…

Date: 2025-04-08

Insufficient CXCL13 secretion in leprosy foamy macrophages attenuates lymphocyte recruitment and antimicrobial protein production

Abstract: Background: Pathogens trigger metabolic reprogramming, leading to the formation of foamy macrophages (FMs). This process provides a favorable environment for bacterial…

Date: 2025-04-08

Assessment of cataract surgery outcomes at Jimma Medical Center, Jimma, Southwest Ethiopia

Abstract: Background: Globally, cataract is the leading cause of blindness accounting for 51% and affecting approximately 39 million people. Visual rehabilitation is achieved…

Date: 2025-04-08

Predicting vessel recanalization in extracranial internal carotid artery dissection: a nomogram based on ultrasonography and clinical features

Abstract: Background: Extracranial internal carotid artery dissection (EICAD) is a prominent factor in ischemic stroke in young patients, and vessel recanalization is correlated…

Date: 2025-04-07

Prognostic significance of serum MUC5AC in resected pancreatic ductal adenocarcinoma: initial insights

Abstract: Background: We investigated the association between serum MUC5AC (sMUC5AC) levels and patient outcomes in individuals who underwent resection for pancreatic ductal…

Date: 2025-04-07

The feasibility and effectiveness of one-puncture of rectus sheath block combined with transverse abdominis plane block in patients undergoing thoracoscopic-laparoscopic radical esophagectomy: a prospective randomized controlled study

Abstract: Background: This study aimed to assess the feasibility and effectiveness of ultrasound-guided one-puncture of rectus sheath block (RSB) combined with the transverse…

Date: 2025-04-07

Development and validation of a disulfidptosis-related genes signature for predicting outcomes and immunotherapy in acute myeloid leukemia

Abstract: Background: Acute myeloid leukemia (AML) is a hematopoietic malignancy with poor outcomes and high recurrence. Disulfidptosis, a novel form of programmed cell death…

Date: 2025-04-04

HLA-mismatched stem cell microtransplant prolonged overall survival and promoted immunological reconstitution for multiple myeloma

Abstract: Background: Despite advances in the treatment of multiple myeloma, a proportion of patients still hardly achieve desired prognosis. Although microtransplant (MST) has…

Date: 2025-04-04