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Pseudomonas aeruginosa enhances anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8+ T cells

Abstract: Background: Immune checkpoint therapy for colorectal cancer (CRC) has been found to be unsatisfactory for clinical treatment. Fecal microbiota transplantation (FMT) has…

Date: 2025-03-21

The impact of depression on the quality of life of lung cancer patients undergoing chemotherapy: mediating effects of perceived social support

Abstract: Background: Quality of life (QOL) in patients undergoing chemotherapy for lung cancer has been a key research area. Numerous studies have examined the relationships…

Date: 2025-03-21

Evaluating the Implementation of fan-beam CT-guided online adaptive re-planning in definitive cervical cancer radiotherapy

Abstract: Background: This study aims to investigate the feasibility of fan-beam computed tomography (FBCT)-guided online adaptive radiotherapy (oART) in radical radiotherapy for…

Date: 2025-03-21

The relationship between dietary inflammatory index in adults and coronary heart disease: from NHANES 1999–2018

Abstract: Background: Previous studies have shown that pro-inflammatory diets increase the risk of coronary heart disease (CHD) and all-cause mortality. The dietary inflammatory…

Date: 2025-03-21

Waist circumference mediates the relationship between atherogenic index of plasma and infertility

Abstract: Background: A newly developed technique, Atherogenic Index of Plasma (AIP), is linked to numerous metabolic disorders. Prior researches have indicated strong correlation…

Date: 2025-03-20

Impact of ESPGHAN no-biopsy strategy on the outcome of celiac disease treatment in children

Abstract: Aim: The European Society for Pediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) allows a no-biopsy diagnostic of celiac disease under certain conditions. We…

Date: 2025-03-20

Two-dimensional speckle tracking of the ascending aorta: a novel approach to evaluate arterial stiffness in pediatric patients with repaired conotruncal anomalies using echocardiography

Abstract: Background: Children with repaired conotruncal abnormalities (CTA) are at risk of progressive aortic dilation and deteriorating aortic elasticity even after surgical…

Date: 2025-03-20

The interpretation of code status concept among pediatric health care workers, a multicenter cross sectional study across Lebanon

Abstract: Background: Cardiopulmonary resuscitation (CPR) use with no considerations given to patient selection or therapeutic aim resulted in extension of the agony, pain and…

Date: 2025-03-20

Symptomatic joint hypermobility is not a barrier to attendance, graduation, or satisfaction for adults participating in a multidisciplinary pain rehabilitation program

Abstract: Introduction: Symptomatic joint hypermobility, as found in conditions like hypermobile Ehlers-Danlos syndrome (hEDS), presents unique challenges in pain management due…

Date: 2025-03-20

Exploring the clinical features of minimally verbal autistic children

Abstract: Introduction: It is recognized that around 25-30% of autistic children do not develop functional speech and remain minimally verbal beyond the age of 5. However, little…

Date: 2025-03-20