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Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21

Abstract: Background: Infantile Epileptic Spasms Syndrome (IESS) is the most common epilepsy syndrome in children with trisomy 21. First-line standard treatments for IESS include…

Date: 2025-02-12

Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker—epicardial adipose tissue mass index: a prospective cohort study

Abstract: Background: Although reperfusion therapy has led to improvements in the acute phase of ST-segment elevation myocardial infarction (STEMI), the incidence of major adverse…

Date: 2025-02-12

Men's more frequent predisposing factors in infectious endocarditis facilitate improvement of outcomes by shortening of diagnostic delay

Abstract: Introduction: Despite growing evidence for sex-specific differences in cardiovascular disease, sex is poorly considered in the management of infectious endocarditis (IE).

Date: 2025-02-12

A within-person investigation of recovery identity following substance use disorder: examining the impact of recovery-focused social contexts

Abstract: Background: The social identity model of recovery (SIMOR) posits that adopting a recovery identity is vital for achieving favorable recovery outcomes. Until now, no…

Date: 2025-02-12

Effects of family socioeconomic status on the self-expectations of children under grandparenting in China

Abstract: Introduction: The increasing expansion of grandparenting necessitates further study of the effects of grandparenting on child development. This study investigated the…

Date: 2025-02-12

Social isolation in the young and middle-aged patients with stroke: role of social support, family resilience and hope

Abstract: Background: Stroke is the leading cause of death and disability among adults in China. Social isolation in stroke survivors is a major public health concern across the…

Date: 2025-02-12

Effectiveness of ertugliflozin during Ramadan fasting in patients with type 2 diabetes mellitus: a real-world study (ErtuRamadan study)

Abstract: Background: Management of type 2 diabetes mellitus (T2DM) during Ramadan fasting presents unique challenges due to prolonged fasting periods, irregular meal schedules,…

Date: 2025-02-11

A Multivariate prediction model for amlodipine therapeutic efficacy in pediatric primary hypertension

Abstract: Background: There are currently no biomarker-based prediction models for amlodipine therapeutic efficacy in pediatric hypertension. This study aimed to identify…

Date: 2025-02-11