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Weight loss-independent changes in human growth hormone during water-only fasting: a secondary evaluation of a randomized controlled trial

Abstract: Introduction: Water-only fasting for one day or more may provide health benefits independent of weight loss. Human growth hormone (HGH) may play a key role in multiple…

Date: 2025-02-07

Efficacy in Japanese adults with growth hormone deficiency receiving weekly somapacitan or daily growth hormone: results from phase 3 REAL 1 trial

Abstract: Introduction: Somapacitan is a long-acting growth hormone (GH) derivative approved for once-weekly treatment of adult GH deficiency (AGHD). This study aimed to evaluate…

Date: 2025-02-07

Characterization of adult T-cell leukemia/lymphoma patients with specific skin lesions in a tertiary dermatological service in Brazil

Abstract: Introduction: Human T-lymphotropic virus type-1 (HTLV-1) is endemic in some countries, including Brazil. HTLV-1 is the etiological agent of adult T-cell…

Date: 2025-02-06

Endocrine and metabolic comorbidities in juvenile-onset systemic lupus erythematosus

Abstract: Background and aims: Juvenile-onset systemic lupus erythematosus (JSLE) is a chronic autoimmune disease affecting individuals under 18, causing multi-system impairment.…

Date: 2025-02-06

Candidate approaches for predicting vitiligo recurrence: an effective model and biomarkers

Abstract: Background: Vitiligo is a challenging chronic condition with unpredictable disease course and high propensity for relapse post-treatment. Recent studies have reported…

Date: 2025-02-06

Global, regional, national prevalence, mortality, and disability-adjusted life-years of cutaneous squamous cell carcinoma and trend analysis from 1990 to 2021 and prediction to 2045

Abstract: Background: A serious worldwide health concern is cutaneous squamous cell carcinoma (cSCC). For the purpose of creating focused strategies, it is essential to comprehend…

Date: 2025-02-06

The association of physical activity and carotid intima-media-thickness in adolescents—data of the prospective early vascular ageing-tyrol cohort study

Abstract: Background: Physical activity (PA) protects against cardiovascular disease. However, previous research has shown that high PA is associated with an increased carotid…

Date: 2025-02-06

Residents as learning facilitators inside and outside of interprofessional education: a faculty development program in postgraduate pediatric training

Abstract: Introduction: Changing learning environments in health professions are an important challenge of interprofessional education (IPE). When students experience IPE…

Date: 2025-02-06

Electrocardiographic signs of cardiac ischemia at rest and during exercise in patients with COPD traveling to 3,100?m: data from a randomized trial of acetazolamide

Abstract: Introduction: In patients with chronic obstructive pulmonary disease (COPD), oxygen delivery to the heart may be impaired during travel at altitude. We assessed…

Date: 2025-02-06