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Molecular landscape of kidney allograft tissues data integration portal (NephroDIP): a curated database to improve integration of high-throughput kidney transplant datasets

Abstract: Introduction: Kidney transplantation is the optimal treatment for end-stage kidney disease; however, premature allograft loss remains a serious issue. While many…

Date: 2024-09-27

Role of disulfidptosis in colorectal adenocarcinoma: implications for prognosis and immunity

Abstract: Background: Recent research has found a new way of cell death: disulfidptosis. Under glucose starvation, abnormal accumulation of disulfide molecules such as Cystine in…

Date: 2024-09-27

The efficacy of curcumin/Qing Dai combination in children with active ulcerative colitis: a multicenter retrospective cohort study

Abstract: Background: Curcumin and Qing Dai (QD) are herbal extracts that recently showed efficacy in treating inflammatory bowel disease (IBD). Since 2016, a combination of…

Date: 2024-09-27

Preoperative predictive model for the probability of lymph node metastasis in gastric cancer: a retrospective study

Abstract: Background: Effectively diagnosing lymph node (LN) metastasis (LNM) is crucial in determining the condition of patients with gastric cancer (GC). The present study was…

Date: 2024-09-27

Clinical performance of a novel and rapid bioassay for detection of thyroid-stimulating immunoglobulins in Graves’ orbitopathy patients: a comparison with two commonly used immunoassays

Abstract: Background: For the selective detection of thyroid-stimulating hormone receptor antibodies with stimulating properties (thyroid-stimulating immunoglobulins; TSI), a…

Date: 2024-09-27

Cognitive impairments in autoimmune encephalitis: the role of autoimmune antibodies and oligoclonal bands

Abstract: Introduction: The presence of oligoclonal bands (OCBs) in cerebrospinal fluid (CSF) is a pivotal diagnostic marker for multiple sclerosis (MS). These bands play a…

Date: 2024-09-27

Lipocalin-2 drives neuropsychiatric and cutaneous disease in MRL/lpr mice

Abstract: Introduction: Approximately 20-40% of patients with systemic lupus erythematosus (SLE) experience neuropsychiatric SLE (NPSLE), which often manifests as cognitive…

Date: 2024-09-27

Nutritional status and dietary habits in older adults with fixed implant dental prostheses: a case-control study

Abstract: Aim: To evaluate the nutritional status, nutritional risk, and dietary habits of patients treated with bimaxillary implant-supported fixed prostheses in comparison with…

Date: 2024-09-26

PD-1 expression in tumor infiltrating lymphocytes as a prognostic marker in early-stage non-small cell lung cancer

Abstract: Introduction: Programmed death ligand – 1 (PD-L1) expression is a well-established predictive biomarker for immunotherapy in non-small cell lung cancer (NSCLC).…

Date: 2024-09-26

Identifying and quantifying initial post-discharge needs for clinical review of sick, newborns in Kenya based on a large multi-site, retrospective cohort study

Abstract: Background: Progress in neonatal care has resulted in a 51% decrease in global neonatal mortality rates from 1990 to 2017. Enhanced survival will put pressure on health…

Date: 2024-09-26