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Risk factors for regional lymph node metastasis in rectal neuroendocrine tumors: a population-based study

Abstract: Introduction: The identification of risk factors for regional lymph node (r-LN) metastasis in rectal neuroendocrine tumors (R-NETs) remains challenging. Our objective…

Date: 2024-09-04

A phase III study to access the safety and efficacy of prolgolimab 250 mg fixed dose administered every 3 weeks versus prolgolimab 1 mg/kg every 2 weeks in patients with metastatic melanoma (FLAT)

Abstract: Background: Prolgolimab is the first Russian PD-1 inhibitor approved for the first-line treatment of unresectable or metastatic melanoma and advanced non-small cell lung…

Date: 2024-09-04

Safety and outcome of children, adolescents and young adults participating in phase I/II clinical oncology trials: a 9-year center experience

Abstract: Introduction: Enrolling children with cancer in early phase trials is crucial to access innovative treatments, contributing to advancing pediatric oncology research and…

Date: 2024-09-04

Association of non-high-density lipoprotein to high-density lipoprotein ratio (NHHR) with prognosis in cancer survivors: a population-based study in the United States

Abstract: Background: Patients with cancer frequently exhibit alterations in serum lipid profiles associated with chemotherapy. It has been reported that lipid distribution in…

Date: 2024-09-04

Integrated transcriptomic analysis and machine learning for characterizing diagnostic biomarkers and immune cell infiltration in fetal growth restriction

Abstract: Background: Fetal growth restriction (FGR) occurs in 10% of pregnancies worldwide. Placenta dysfunction, as one of the most common causes of FGR, is associated with…

Date: 2024-09-04

Predictors of sleepiness in a large-scale epidemiology study ESSE-RF

Abstract: Introduction: To identify predictors of excessive daytime sleepiness we analyzed data from the ‘Epidemiology of cardiovascular diseases in regions of Russia (ESSE-RF)’…

Date: 2024-09-04

Assessment of sociodemographic and psychiatric characteristics of transgender adults seen at a Midwest tertiary medical center

Abstract: Background: The National Academy of Medicine has formally identified transgender adults as an understudied population in critical need of health research. While national…

Date: 2024-09-04

Minimum acceptable diet use and its associated factors among children aged 6–23 in Ghana: a mixed effect analysis using Ghana Demographic and Health Survey

Abstract: Introduction: Inappropriate feeding practices are a major contributor to child malnutrition. To monitor the feeding practices of young children, current and frequent…

Date: 2024-09-04

The nutritional and feeding status of children living in selected residential child care facilities in Zambia: implications for programs and policies

Abstract: Introduction: This study aimed to estimate the prevalence of undernutrition and risk of feeding difficulties and describe common feeding practices for children from…

Date: 2024-09-04

Disability health in medical education: development, implementation, and evaluation of a pilot curriculum at Stanford School of Medicine

Abstract: Background: People with disabilities face significant healthcare disparities due to barriers to accessing care, negative attitudes of providers, and lack of education on…

Date: 2024-09-04