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Bioactivity-guided isolation of potential antidiarrheal constituents from Euphorbia hirta L. and molecular docking evaluation

Abstract: Background: Euphorbia hirta L., a member of the Euphorbiaceae family, is extensively used as a folk medicine across various regions. In China, its decoction is…

Date: 2024-08-29

Short- and long-term impacts of the National Essential Medicines Policy on drug availability, price, and usage in a deprived rural county in southwestern China: an interrupted time series analysis across 8?years

Abstract: Background: China’s National Essential Medicines Policy (NEMP) has been implemented for over 15?years; yet empirical evidence on its long-term impacts is lacking,…

Date: 2024-08-29

Health-related quality of life and associated factors in heart failure with reduced ejection fraction patients at University of Gondar Hospital, Ethiopia

Abstract: Introduction: Living with heart failure poses challenges due to its poor prognosis and impact on quality of life, making it crucial to assess how it affects patients for…

Date: 2024-08-29

Influencing factors on the quality of recovery after total knee arthroplasty: development of a predictive model

Abstract: Introduction: Total Knee Arthroplasty (TKA) is a widely performed procedure that significantly benefits patients with severe knee degeneration. However, the recovery…

Date: 2024-08-29

Evaluation of good review practices in member authorities of the East African Medicines Regulatory Harmonisation initiative: strategies for alignment with African medicines agency

Abstract: Introduction: The East African Community Medicines Regulatory Harmonisation (EAC-MRH) programme was established to address challenges faced by national regulatory…

Date: 2024-08-29

Relationship between urban green space and mental health in older adults: mediating role of relative deprivation, physical activity, and social trust

Abstract: Introduction: The importance of improving older adults' mental health is increasing worldwide with the rapid development of the aging process. Green space is an…

Date: 2024-08-29

Is minimally invasive multi-vessel off-pump coronary surgery as safe and effective as MIDCAB?

Abstract: Introduction: The safety and efficacy of minimally invasive direct coronary artery bypass (MIDCAB) surgery has been confirmed in numerous reports. However, minimally…

Date: 2024-08-29

Antigen-specific T helper cells and cytokine profiles predict intensity and longevity of cellular and humoral responses to SARS-CoV-2 booster vaccination

Abstract: Introduction: Pre-existent pools of coronavirus-specific or cross-reactive T cells were shown to shape the development of cellular and humoral immune responses after…

Date: 2024-08-29