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Radiation and systemic immunotherapy for metastatic uveal melanoma: a clinical retrospective review

Abstract: Introduction: Metastatic uveal melanoma (mUM) is a difficult to treat disease. The liver is the primary site of metastasis in most patients, though uveal melanoma…

Date: 2024-07-04

Unraveling the role of Major Vault Protein as a novel immune-related biomarker that promotes the proliferation and migration in pancreatic adenocarcinoma

Abstract: Background: Pancreatic adenocarcinoma (PAAD) is a formidable challenge in oncology research, with a complex pathogenesis that requires to be explored. Major Vault…

Date: 2024-07-04

Diagnosis of Brugada syndrome affects quality of life and psychological status

Abstract: Background: Chronic diseases have a negative impact on quality of life (QOL) and psychological health. There are limited related data regarding this topic in Brugada…

Date: 2024-07-03

Vortioxetine treatment for neuropathic pain in major depressive disorder: a three-month prospective study

Abstract: Introduction and objective: Several studies revealed the therapeutic potential of vortioxetine (Vo) for pain. In this context, we aimed to evaluate the efficacy of Vo as…

Date: 2024-07-03

A network analysis of the interrelationships between depression, anxiety, insomnia and quality of life among fire service recruits

Abstract: Background: Research on the mental health and quality of life (hereafter QOL) among fire service recruits after the end of the COVID-19 restrictions is lacking. This…

Date: 2024-07-03

Transcriptome analysis combined with Mendelian randomization screening for biomarkers causally associated with diabetic retinopathy

Abstract: Background: Diabetic retinopathy (DR) is considered one of the most severe complications of diabetes mellitus, but its pathogenesis is still unclear. We hypothesize that…

Date: 2024-07-03