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Efficacy of anti-PD-1 monotherapy for recurrent or metastatic olfactory neuroblastoma

Abstract: Background: Olfactory neuroblastoma (ONB) is a rare malignant tumor of the head and neck. Due to its rarity, standard systemic therapy for this condition has yet to be…

Date: 2024-05-23

Proof-of-concept for an automatable mortality prediction scoring in hospitalised older adults

Abstract: Introduction: It is challenging to prognosticate hospitalised older adults. Delayed recognition of end-of-life leads to failure in delivering appropriate palliative care…

Date: 2024-05-23

Mendelian randomization shows causal effects of birth weight and childhood body mass index on the risk of frailty

Abstract: Background: The association between birth weight and childhood body mass index (BMI) and frailty has been extensively studied, but it is currently unclear whether this…

Date: 2024-05-23

Blood cell indices and inflammation-related markers with kidney cancer risk: a large-population prospective analysis in UK Biobank

Abstract: Background: Kidney cancer is a prevalent malignancy with an increasing incidence worldwide. Blood cell indices and inflammation-related markers have shown huge potential…

Date: 2024-05-23

Timing matters? The effects of two different timing of high protein diets on body composition, muscular performance, and biochemical markers in resistance-trained males

Abstract: Background: It is unclear whether resistance training in combination with different timing of protein intake might have differential effects on muscle hypertrophy,…

Date: 2024-05-23

Association of body mass index with rapid eye movement sleep behavior disorder in Parkinson’s disease

Abstract: Background: The association between body mass index (BMI) and rapid eye-movement (REM) sleep-related behavioral disorder (RBD) in Parkinson’s disease (PD) remains…

Date: 2024-05-23

Effects of Baduanjin exercise on cognitive frailty, oxidative stress, and chronic inflammation in older adults with cognitive frailty: a randomized controlled trial

Abstract: Background: Oxidative stress and chronic inflammation play an important role in the pathogenesis process of cognitive frailty (CF). Regular Baduanjin exercise could…

Date: 2024-05-23

Metabolic syndrome and pharmacotherapy outcomes in patients with type 2 diabetes mellitus

Abstract: Background: Metabolic syndrome is a group of metabolic abnormalities that increase predisposition to several diseases including ischemic heart disease and diabetes…

Date: 2024-05-23