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Genetically predicted N-methylhydroxyproline levels mediate the association between naive CD8+ T cells and allergic rhinitis: a mediation Mendelian randomization study

Abstract: Background: Allergic rhinitis (AR), a prevalent chronic inflammatory condition triggered by immunoglobulin E (IgE), involves pivotal roles of immune and metabolic…

Date: 2024-05-23

Anti-RBD IgG antibodies from endemic coronaviruses do not protect against the acquisition of SARS-CoV-2 infection among exposed uninfected individuals

Abstract: Background: The Coronaviridae family comprises seven viruses known to infect humans, classified into alphacoronaviruses (HCoV-229E and HCoV-NL63) and betacoronaviruses…

Date: 2024-05-23

Is gender dysphoria associated with increased hospital cost per stay among patients hospitalized for depression? Focus on the racial and regional variance in US hospitals

Abstract: Introduction: Individuals with gender dysphoria do not identify with their sex assigned at birth and face societal and cultural challenges, leading to increased risk for…

Date: 2024-05-23

Parental acceptance of brain health programs for preschool children: a mixed-methods study exploring barriers, facilitators and future approaches

Abstract: Background: Recent research proposes that as much as 40% of dementia risk is amendable. Promoting healthy lifestyle behaviors in early life through educational methods…

Date: 2024-05-23

Effects of rope skipping exercise on working memory and cardiorespiratory fitness in children with attention deficit hyperactivity disorder

Abstract: Introduction: Children with Attention Deficit Hyperactivity Disorder (ADHD) exhibit deficits in working memory (WM) and cardiorespiratory fitness (CRF), both of which…

Date: 2024-05-23

Responsiveness and construct validity of two outcome measures of bilateral upper limb function in patients with chronic stroke

Abstract: Background: Stroke is a leading cause of long-term disability among stroke survivors. Despite the availability of numerous stroke rehabilitative therapies, such as…

Date: 2024-05-23

The long noncoding RNA SUMO1P3 as urinary biomarker for monitoring bladder cancer progression

Abstract: Introduction: Urothelial Bladder Cancer (BC) is the ninth most common cancer worldwide. It is classified into Non Muscle Invasive (NMIBC) and Muscle Invasive Bladder…

Date: 2024-05-23

Can major public health emergencies increase the participation of commercial insurance? Evidence from China

Abstract: Background: Public health emergencies have a lasting impact on a country's economic and social development. However, commercial insurance can disperse these negative…

Date: 2024-05-23

A Lifelike guided journey through the pathophysiology of pulmonary hypertension—from measured metabolites to the mechanism of action of drugs

Abstract: Introduction: Pulmonary hypertension (PH) is a pathological condition that affects approximately 1% of the population. The prognosis for many patients is poor, even…

Date: 2024-05-23