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Mediators between body mass index and atrial fibrillation: a Mendelian randomization study

Abstract: Background: Although obesity is a recognized risk factor of atrial fibrillation (AF), the mechanisms are not fully understood.

Date: 2024-05-22

Evolving migraine management: Lithuania's telemedicine experience

Abstract: Introduction: COVID-19 challenges have underscored the potential of telemedicine in migraine management. This study focuses on assessing patients' telemedicine…

Date: 2024-05-22

Enhancing ASPP2 promotes acute liver injury via an inflammatory immunoregulatory mechanism

Abstract: Background: Acute liver injury (ALI), which is a type of inflammation-mediated hepatocellular injury, is a clinical syndrome that results from hepatocellular apoptosis…

Date: 2024-05-22

Sex differences in immune protection in mice conferred by heterologous vaccines for pneumonic plague

Abstract: Background: Yersinia pestis is the etiological agent of plague, which can manifest as bubonic, septicemic, and/or pneumonic disease. Plague is a severe and rapidly…

Date: 2024-05-21

A ferritin nanoparticle vaccine based on the hemagglutinin extracellular domain of swine influenza A (H1N1) virus elicits protective immune responses in mice and pigs

Abstract: Introduction: Swine influenza viruses (SIVs) pose significant economic losses to the pig industry and are a burden on global public health systems. The increasing…

Date: 2024-05-21

Causal association between type 2 diabetes mellitus and acute suppurative otitis media: insights from a univariate and multivariate Mendelian randomization study

Abstract: Background: Type 2 diabetes mellitus (T2DM) and hearing loss (HL) constitute significant public health challenges worldwide. Recently, the association between T2DM and…

Date: 2024-05-21

Cynaroside ameliorates methotrexate-induced enteritis in rats through inhibiting NLRP3 inflammasome activation

Abstract: Introduction: Cynaroside exhibits various biological properties, including anti-inflammatory, antiviral, antitumor, and cardioprotective effects. However, its…

Date: 2024-05-21

Acute hematologic toxicity prediction using dosimetric and radiomics features in patients with cervical cancer: does the treatment regimen matter?

Abstract: Background: Acute hematologic toxicity (HT) is a prevalent adverse tissue reaction observed in cervical cancer patients undergoing chemoradiotherapy (CRT), which may…

Date: 2024-05-21

Biologics targeting IL-17 sharply reduce circulating T follicular helper and T peripheral helper cell sub-populations in psoriasis

Abstract: Introduction: Circulating T follicular helper (cTfh) cells and circulating T peripheral helper (cTph) cells (which share common characteristics with the cTfh population)…

Date: 2024-05-21