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Obesity-related knowledge, attitude, and practices among primary care physicians in China: a cross-sectional study

Abstract: Obesity is a major global public health crisis but remains inadequately addressed during clinical encounters. In China, the primary healthcare system plays a vital role…

Date: 2025-09-25

Association of acyl-CoA oxidase-like gene polymorphisms with risk, onset age, and beta-cell function of type 1 diabetes in Chinese

Abstract: Genome-wide association studies in Caucasians suggested an association between the acyl-CoA oxidase-like ( ACOXL ) gene and type 1 diabetes (T1D). We investigated if…

Date: 2025-09-25

Contrasting associations of body mass index and waist circumference with cancer incidence in the elderly: a nationwide population-based study

Abstract: Obesity has been reported to be associated with increased cancer risk. Body mass index (BMI) and waist circumference (WC) are representative measures of adiposity, but…

Date: 2025-09-25

Human milk-derived 5?-UMP promotes thermogenesis and mitochondrial biogenesis to ameliorate obesity

Abstract: Traditional obesity interventions are often unsuitable for children. Breastfeeding has been shown to reduce obesity risk, potentially through bioactive metabolites in…

Date: 2025-09-25

Diagnostic and therapeutic pitfalls in the management of pediatric patients with 3?-hydroxysteroid dehydrogenase type 2 (3?-HSD2) deficiency - a single center experience

Abstract: Congenital adrenal hyperplasia (CAH) due to 3?-hydroxysteroid dehydrogenase type 2 deficiency (3?-HSD2D) is an exceptionally rare disorder affecting adrenal…

Date: 2025-09-25

Unveiling new insights: a comprehensive questionnaire-based single-center study of sebaceous nevus

Abstract: Sebaceous nevus (SN) is a rare, benign, congenital tumor. There is limited information on its clinical features, familial influences, quality of life (QoL) impact, and…

Date: 2025-09-25

Leveraging anatomy to improve safety and efficacy in temple augmentations—a case series of 20 patients

Abstract: Temple augmentation has become a cornerstone in full-face aesthetic rejuvenation, yet traditional techniques often face limitations, including aesthetic limitations and…

Date: 2025-09-25

H3K27me3 and HOXA9 expression predict prognosis in pediatric acute myeloid leukemia: an epigenetic-transcriptional correlation study

Abstract: Epigenetic dysregulation plays a central role in pediatric acute myeloid leukemia (AML), yet its clinical relevance remains underexplored. This study primarily aimed to…

Date: 2025-09-25

Clinical, immunological, molecular characteristics and outcomes of stem cell transplantation in ZAP70 deficiency: a single-center experience

Abstract: Zeta-chain-associated protein kinase 70 ( ZAP70 ) deficiency is a rare autosomal recessive T + B + NK + combined immunodeficiency characterized by heterogeneous clinical…

Date: 2025-09-25

Application of drug-induced sleep endoscopy in infants with dynamic upper airway collapse

Abstract: The study aimed to evaluate the utility and safety of drug-induced sleep endoscopy (DISE) in infants with suspected dynamic upper airway collapse. Infants with suspected…

Date: 2025-09-25