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Exercise therapy for knee osteoarthritis pain: how does it work? A study protocol for a randomised controlled trial

Abstract: Introduction Muscle strengthening training (MST) and behavioural graded activity (BGA) show comparable effects on knee osteoarthritic (KOA) pain, but the mechanisms of…

Date: 2024-01-10

Predictive factors for the treatment success of peri-implantitis: a protocol for a prospective cohort study

Abstract: Introduction Peri-implantitis, a common biological complication of dental implant, has attracted considerable attention due to its increasing prevalence and limited…

Date: 2024-01-10

Psychometric properties of the living with long term conditions scale in an English-speaking population living with long term conditions in the UK

Abstract: Objective To present the psychometric properties of the living with long-term condition (LwLTCs) scale in an English-speaking population of people with different LTCs.…

Date: 2024-01-10

Integrating 4 methods to evaluate physical function in patients with cancer (In4M): protocol for a prospective cohort study

Abstract: Introduction Accurate, patient-centred evaluation of physical function in patients with cancer can provide important information on the functional impacts experienced by…

Date: 2024-01-10

Comparing the efficacy and safety of three surgical approaches for total hysterectomy (TSATH): protocol for a multicentre, single-blind, parallel-group, randomised controlled trial

Abstract: Introduction Hysterectomy is the most common surgical procedure in the field of gynaecology. The traditional multiport laparoscopy, transumbilical laparoendoscopic…

Date: 2024-01-10

Wearables for early detection of atrial fibrillation and timely referral for Indigenous people ?55 years: mixed-methods protocol

Abstract: Introduction Digital health technologies have the potential to provide cost-effective care to remote and underserved populations. To realise this potential, research…

Date: 2024-01-10

Protocol for the challenge non-typhoidal Salmonella (CHANTS) study: a first-in-human, in-patient, double-blind, randomised, safety and dose-escalation controlled human infection model in the UK

Abstract: Introduction Invasive non-typhoidal Salmonella (iNTS) serovars are a major cause of community-acquired bloodstream infections in sub-Saharan Africa (SSA). In this…

Date: 2024-01-10

Protection against Incidences of Serious Cardiovascular Events Study with daily fish oil supplementation in dialysis patients (PISCES): protocol for a randomised controlled trial

Abstract: Introduction Patients with kidney failure with replacement therapy (KFRT) suffer premature cardiovascular (CV) mortality and events with few proven pharmacological…

Date: 2024-01-10

Feasibility and acceptability of offering breast cancer risk assessment to general population women aged 30–39 years: a mixed-methods study protocol

Abstract: Introduction Breast cancer incidence starts to increase exponentially when women reach 30–39 years, hence before they are eligible for breast cancer screening. The…

Date: 2024-01-10