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Deciphering the regulatory mechanisms of honeysuckle ( Lonicera japonica ) on lipopolysaccharide-induced inflammatory responses in loach ( Misgurnus anguillicaudatus ) through small RNA sequencing

Abstract: This study investigates the immunomodulatory effects of Lonicera japonica Thunb. extract, a perennial semi-evergreen vine of the Caprifoliaceae family, on…

Date: 2025-09-23

Morphometric MRI findings in patients with suspected autoimmune psychosis spectrum syndromes and association with EEG slowing, CSF changes, and psychometric/neuropsychological findings

Abstract: Patients with autoimmune encephalitis – who often have accompanying psychiatric symptoms – frequently have electroencephalography (EEG) changes and normal conventional…

Date: 2025-09-23

Association of serum complement C3 level with disease severity in primary pterygium

Abstract: To investigate whether various systemic inflammatory and immunologic markers—including complement C3, C4, antinuclear antibodies (ANA), rheumatoid factor (RF), and other…

Date: 2025-09-23

Association of triglyceride glucose body mass index with osteoporosis risks in a large Chinese adult cohort

Abstract: Insulin resistance (IR) is implicated in bone metabolism dysregulation, but the role of Triglyceride Glucose Body Mass Index (TyG-BMI), a surrogate marker integrating…

Date: 2025-09-23

Predictive factors and outcomes of immune-related adverse events in Chinese patients treated with immune checkpoint inhibitors: a real-world retrospective study

Abstract: The widespread clinical application of immune checkpoint inhibitors (ICIs) has brought immune-related adverse events (irAEs) to the forefront of oncology management.…

Date: 2025-09-23

Nomogram model for prognosis of early colorectal cancer after endoscopic therapy: integration of intestinal microbiota and clinicopathological parameters

Abstract: To integrate the characteristics of intestinal flora and clinical pathological parameters in patients with early colorectal cancer, and to construct and validate a…

Date: 2025-09-23

Identification of shared biomarkers and potential therapeutic targets for antiphospholipid syndrome and recurrent miscarriage by integrated bioinformatics analysis and machine learning

Abstract: Antiphospholipid syndrome (APS) is a group of clinical syndromes of thrombosis or adverse pregnancy outcomes caused by antiphospholipid antibodies that can increase the…

Date: 2025-09-23

The global epidemiology of gastrointestinal cancers attributable to high-BMI: findings from the Global Burden of Disease Study 2021

Abstract: Gastrointestinal (GI) cancers collectively account for over 30% of global cancer-related mortalities. Obesity is a well-established risk factor for GI cancers. We aim to…

Date: 2025-09-23

Identification of anti-mouse PD-1 agonist antibodies that inhibit T cell activation

Abstract: PD-1-stimulating agents have been projected to be unique immunosuppressants for the treatment of undesirable inflammatory conditions including autoimmune diseases. We…

Date: 2025-09-23

Comparison of food extraction techniques and impact of nitrogen fertilization on the potential allergenicity of soybean related to birch pollen-food allergy syndrome

Abstract: Birch pollen-food allergy syndrome is triggered by cross-reactive allergens in plant-based foods. Environmental factors such as nitrogen fertilization may influence food…

Date: 2025-09-23