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The ProCVT smart-sheet as a new screening tool for cardiovascular autonomic neuropathy: a feasibility study

Abstract: Cardiovascular autonomic neuropathy (CAN) is a severe complication of diabetes that impairs the regulation of the cardiovascular system. This can cause hemodynamic…

Date: 2025-10-21

Low-dose vs. standard-dose alteplase for acute ischemic stroke: a real-world single-center retrospective study

Abstract: To investigate the real-world usage patterns and clinical outcomes of low-dose (0.6?mg/kg) versus standard-dose (0.9?mg/kg) intravenous alteplase in patients with acute…

Date: 2025-10-21

Predictors of unplanned hospital readmissions and emergency department revisits in patients with acute ischemic stroke

Abstract: We aim to identify factors associated with emergency department (ED) revisits and hospital readmissions after acute ischemic stroke (AIS) diagnosis and to determine if…

Date: 2025-10-21

Interpretable machine learning for predicting early neurological deterioration in symptomatic intracranial atherosclerotic stenosis

Abstract: To develop and validate a machine learning (ML) model for early neurological deterioration (END) risk prediction in patients with symptomatic intracranial…

Date: 2025-10-21

Edaravone Dexborneol in acute ischemic stroke patients treated with combined intravenous thrombolysis and mechanical thrombectomy for large vessel occlusion

Abstract: Mechanical thrombectomy (MT), when combined with intravenous thrombolysis (IVT), has emerged as an effective therapeutic strategy for acute ischemic stroke (AIS).…

Date: 2025-10-21

Efficacy and safety of intravenous tenecteplase thrombolysis in diffusion-weighted imaging-negative posterior circulation ischemic stroke

Abstract: Clear evidence supporting thrombolytic therapy in diffusion-weighted imaging (DWI)-negative posterior circulation ischemic stroke (PCIS) is lacking. We aimed to…

Date: 2025-10-21

Colonoscopy outcomes of primary screening negative participants highlight the missed diagnosis problem of colorectal cancer screening: an observational study from Yuexiu district in Guangzhou, China

Abstract: False negatives in colorectal cancer (CRC) screening remained a widespread concern, particularly given the notable incidence of false negative results from fecal…

Date: 2025-10-21

Establishment and comparison of three fear of progression risk prediction models for gynecological malignancies patients based on machine learning

Abstract: This study applied the Society Ecosystems Theory to investigate Fear of Progression (FoP) prevalence and predictors in gynecological malignancy patients. By constructing…

Date: 2025-10-21

Comparison of adverse events between intensity-modulated radiation therapy and tomotherapy for early stage breast cancer: a retrospective cohort study

Abstract: Early stage breast cancer treated with adjuvant radiotherapy with two different techniques, tomotherapy (TOMO) and intensity-modulated radiation therapy (IMRT), and…

Date: 2025-10-21

MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis

Abstract: Major Facilitator Superfamily Domain-containing 12 (MFSD12) has emerged as a critical transmembrane protein with increasingly recognized roles in various cancers. The…

Date: 2025-10-21