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CT-Based assessment of sarcopenia and its association with biologic treatment outcomes in Chinese Children with Crohn's disease

Abstract: Sarcopenia affects treatment outcomes in patients with Crohn's disease (CD), yet research focusing on pediatric populations is limited. This study aimed to determine the…

Date: 2025-10-20

Dietary patterns and quality of life among night-shift nurses in tertiary hospitals in Hangzhou: a cross-sectional analysis

Abstract: This study aimed to examine the dietary patterns of nurses working night shifts in tertiary hospitals in Hangzhou and to assess the association between these patterns…

Date: 2025-10-20

Analysis of influencing factors and paths of social frailty in older adult patients with ischemic stroke: a cross-sectional study

Abstract: Analysis of influencing factors and action pathways of social frailty in older adult patients with ischemic stroke. A cross-sectional study was conducted among older…

Date: 2025-10-20

Polysialic acid restrains inflammatory monocyte maturation

Abstract: Sialic acids are widely distributed monosaccharides in the central nervous system (CNS), where they are predominantly found as terminal sialic acid residues, as well as…

Date: 2025-10-20

Deep medullary veins disruption in cerebral small vessel disease: links to AI-quantified lesions and cognitive decline

Abstract: The relationship between cerebral small vessel diseases (CSVD) and deep medullary veins (DMV) has been the subject of only a limited number of studies to date, with the…

Date: 2025-10-20

Efficacy and safety of idebenone tablets in patients with post-stroke cognitive impairment: a real-world study

Abstract: To evaluate the efficacy, safety, and adherence of idebenone tablets in improving cognitive function among patients with post-stroke cognitive impairment in a real-world…

Date: 2025-10-20

Individualized psychotherapy reveals a very high prevalence of adverse life events in functional neurological disorders

Abstract: Adverse life events are frequent in patients with functional neurological disorder (FND), although their prevalence is highly variable when assessed using standardized…

Date: 2025-10-20

Plasma branched-chain amino acids and risk of radiation-induced acute skin toxicity in women with breast cancer: results from the ATHENA project

Abstract: Little is known regarding the influence of circulating plasma branched-chain amino acids (BCAAs) such as leucine, isoleucine, and valine on acute skin toxicity (AST)…

Date: 2025-10-20

Differential diagnosis of eczema and psoriasis using routine clinical data and machine learning: development of a web-based tool in a multicenter outpatient cohort

Abstract: Eczema and psoriasis are common chronic dermatoses with overlapping features, making early differential diagnosis difficult. While biopsy is the gold standard, its…

Date: 2025-10-17

Psoriasis vulgaris leaves a dynamic imprint on circulating and skin ?? TCR repertoires shaped by disease severity, age, and sex

Abstract: Psoriasis vulgaris (PV) is a common, T cell mediated dermatosis with substantial systemic footprint. While ?? T cells are well established drivers of PV, the role of ??…

Date: 2025-10-17