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Development and internal validation of triage-stage prediction models for short-term critical outcomes among adult emergency department patients entering observation or hospital-based care: a retrospective study

Abstract: Risk stratification at emergency department triage may help identify patients who require closer assessment or monitoring. However, prediction models that rely only on…

Date: 2026-10-07

Cardiac troponin T and 28-day mortality in traumatic brain injury: a retrospective cohort study and machine learning prediction model

Abstract: Traumatic brain injury (TBI) frequently induces cardiac dysfunction via the brain-heart axis, yet the prognostic value of cardiac troponin T (cTnT) in TBI remains…

Date: 2026-10-07

Measuring residents’ perceptions of social-ecological healthy communities: development and initial psychometric evaluation of a multidimensional scale

Abstract: Effective community health promotion requires information about residents’ health-related characteristics and the interpersonal, environmental, organizational, and…

Date: 2026-10-07

Spatial organization of neutrophil and macrophage populations in surgically treated hepatocellular carcinoma: a practical tissue-based immunophenotyping study

Abstract: Hepatocellular carcinoma (HCC) has a spatially heterogeneous immune microenvironment, but the compartment-specific distribution of tumor-associated neutrophils (TANs)…

Date: 2026-10-07

BCL2A1 marks an early, less-exhausted CD8 + tumor-infiltrating lymphocyte state associated with PD-1 blockade response in NSCLC

Abstract: The tumor microenvironment exerts intense survival pressure on CD8 + tumor-infiltrating lymphocytes (TILs), yet the cellular basis for an earlier, less-exhausted state…

Date: 2026-10-07

LASSO-based nomogram to predict early treatment failure in advanced hepatocellular carcinoma treated with SBRT, lenvatinib, and tislelizumab

Abstract: Stereotactic body radiotherapy (SBRT) combined with lenvatinib and tislelizumab has shown potential activity in advanced hepatocellular carcinoma (HCC), but early…

Date: 2026-10-07

Higher fibrosis-4 index is associated with 2-year cardiovascular events in Vietnamese adults with type 2 diabetes mellitus: a prospective cohort study

Abstract: Cardiovascular disease is a major extrahepatic outcome in type 2 diabetes mellitus (T2DM) and metabolic fatty liver disease, but prospective data integrating transient…

Date: 2026-10-07

Artificial intelligence for ultrasound-based differentiation of soft tissue liposarcoma from benign masses

Abstract: Accurate preoperative differentiation of liposarcoma from benign masses on ultrasound remains challenging and operator-dependent. We aimed to develop and validate a deep…

Date: 2026-10-07

Liraglutide reduces lipid accumulation in human orbital fibroblasts in Graves’ orbitopathy

Abstract: Graves’ orbitopathy (GO) is characterized by proliferation and differentiation of orbital fibroblasts. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely…

Date: 2026-10-07

Analysis of health risk factors in the petroleum and petrochemical industry: a comprehensive study based on the analytic hierarchy process and delphi method

Abstract: This study integrates the Delphi method with the Analytic Hierarchy Process (AHP) to identify, refine, and prioritize occupational health risk factors in the petroleum…

Date: 2026-10-07