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From psoriasis to psoriatic arthritis: epidemiological insights from a retrospective cohort study of 74,046 patients

Abstract: Introduction: To verify our hypothesis that psoriatic arthritis (PsA) is mainly genetically predetermined and distinct from psoriasis (PsO), we use the TriNetX database…

Date: 2024-06-27

Relationship between serum inflammatory cytokines and suicide risk in patients with major depressive disorder

Abstract: Background: Studies have shown that increased inflammatory cytokines are associated with suicide risk, but the relationship between suicide risk and inflammatory…

Date: 2024-06-27

Psychological dimensions in alcohol use disorder: comparing active drinkers and abstinent patients

Abstract: Background: Alcohol use disorder (AUD) is a major public health concern due to its various physical, psychological, and social consequences. Despite regulatory…

Date: 2024-06-27

Identification and validation of cuproptosis-related genes in acetaminophen-induced liver injury using bioinformatics analysis and machine learning

Abstract: Background: Acetaminophen (APAP) is commonly used as an antipyretic analgesic. However, acetaminophen overdose may contribute to liver injury and even liver failure.…

Date: 2024-06-27

Impact of in-utero exposure to HIV and latent TB on infant humoral responses

Abstract: Introduction: Latent tuberculosis infection (LTBI) is a common coinfection in people living with HIV (PWH). How LTBI and HIV exposure in utero influence the development…

Date: 2024-06-27

Tumor Treating Fields (TTFields) induce homologous recombination deficiency in ovarian cancer cells, thus mitigating drug resistance

Abstract: Background: Ovarian cancer is the leading cause of mortality among gynecological malignancies. Carboplatin and poly (ADP-ribose) polymerase inhibitors (PARPi) are often…

Date: 2024-06-27

Same-day discharge after percutaneous closure of persistent foramen ovale using intracardiac echocardiography and the Gore Septal Occluder

Abstract: Aim: Periprocedural and postinterventional care of patients undergoing closure of patent foramen ovale (PFO) varies significantly across care providers. Same-day…

Date: 2024-06-26

Emotion-related impulsivity and suicidal ideation and behavior in schizophrenia spectrum disorder: a pilot fMRI study

Abstract: Introduction: Suicidal ideation and behavior (SIB) are serious problems in people with schizophrenia spectrum disorders (SSD). Nevertheless, relatively little is known…

Date: 2024-06-26