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The effects of venlafaxine on depressive-like behaviors and gut microbiome in cuprizone-treated mice

Abstract: Background: Cuprizone (CPZ)-treated mice show significant demyelination, altered gut microbiome, and depressive-like behaviors. However, the effects of venlafaxine (Ven)…

Date: 2024-06-03

Quality of life and mental health status of glaucoma patients

Abstract: Introduction: Glaucoma, a leading cause of irreversible blindness worldwide, poses significant challenges to patients’ quality of life (QOL) and mental well-being.

Date: 2024-06-03

Comparison of the efficacy of ROI-C cage with Zero-P device in anterior cervical discectomy and fusion of cervical degenerative disc disease: a two-year follow-up study

Abstract: Background: This study aimed to compare the clinical outcomes of Zero-P and ROI-C devices applied to anterior cervical discectomy and fusion (ACDF) surgery of cervical…

Date: 2024-06-03

Distinct TB-antigen stimulated cytokine profiles as predictive biomarkers for unfavorable treatment outcomes in pulmonary tuberculosis

Abstract: Introduction: The assessment of tuberculosis (TB) treatment outcomes predominantly relies on sputum culture conversion status. To enhance treatment management, it is…

Date: 2024-06-03

Transcriptional and functional remodeling of lung-resident T cells and macrophages by Simian varicella virus infection

Abstract: Introduction: Varicella zoster virus (VZV) causes varicella and can reactivate as herpes zoster, and both diseases present a significant burden worldwide. However, the…

Date: 2024-06-03

Value of catecholamine levels in the differential diagnosis of vasovagal syncope and psychogenic pseudosyncope in children

Abstract: Background and purpose: Vasovagal syncope (VVS) and psychogenic pseudosyncope (PPS) can be difficult to distinguish, given their similar clinical presentations. This…

Date: 2024-05-31

Exploratory metabolomic analysis for characterizing the metabolic profile of the urinary bladder under estrogen deprivation

Abstract: Background: Estrogen homeostasis is crucial for bladder function, and estrogen deprivation resulting from menopause, ovariectomy or ovarian dysfunction may lead to…

Date: 2024-05-31

Correlation between serum phosphate and all-cause mortality in critically ill patients with coronary heart disease accompanied by chronic kidney disease: a retrospective study using the MIMIC-IV database

Abstract: Background: The adverse clinical endpoints of cardiovascular and kidney diseases are correlated with increased serum phosphate levels. However, in critically ill…

Date: 2024-05-31

The associations between dietary flavonoid intake and hyperlipidemia: data from the national health and nutrition examination survey 2007–2010 and 2017–2018

Abstract: Background: Hyperlipidemia is a worldwide health problem and a significant risk factor for cardiovascular diseases; therefore, it imposes a heavy burden on society and…

Date: 2024-05-31

Potential molecular and cellular mechanisms of the effects of cuproptosis-related genes in the cardiomyocytes of patients with diabetic heart failure: a bioinformatics analysis

Abstract: Background: Diabetes mellitus is an independent risk factor for heart failure, and diabetes-induced heart failure severely affects patients’ health and quality of life.…

Date: 2024-05-31