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Comprehensive machine learning models for predicting therapeutic targets in type 2 diabetes utilizing molecular and biochemical features in rats

Abstract: Introduction: With the increasing prevalence of type 2 diabetes mellitus (T2DM), there is an urgent need to discover effective therapeutic targets for this complex…

Date: 2024-05-24

Marine microalgae Schizochytrium demonstrates strong production of essential fatty acids in various cultivation conditions, advancing dietary self-sufficiency

Abstract: Introduction: Polyunsaturated fatty acids (PUFAs) are essential nutrients that humans obtain from their diet, primarily through fish oil consumption. However, fish oil…

Date: 2024-05-24

Predictive model of suicide risk in Colombian university students: quantitative analysis of associated factors

Abstract: Introduction: The risk of suicide and completed suicides among young university students presents critical challenges to mental and public health in Colombia and…

Date: 2024-05-24

Determining diagnostic delays in Romanian multiple myeloma patients using the Aarhus statement

Abstract: Introduction: Multiple Myeloma (MM) is classified as one of the most challenging cancers to diagnose, and the hematological malignancy is associated with prolonged…

Date: 2024-05-24

Integrative analysis of COL6A3 in lupus nephritis: insights from single-cell transcriptomics and proteomics

Abstract: Introduction: Lupus nephritis (LN), a severe complication of systemic lupus erythematosus (SLE), presents significant challenges in patient management and treatment…

Date: 2024-05-24

Development and validation of nomogram to predict overall survival and disease-free survival after surgical resection in elderly patients with hepatocellular carcinoma

Abstract: Background: Hepatocellular carcinoma (HCC) is one of the common causes of tumor death in elderly patients. However, there is a lack of individualized prognostic…

Date: 2024-05-24

The safety and feasibility of laparoscopic anatomical left hemihepatectomy along the middle hepatic vein from the head side approach

Abstract: Background: Laparoscopic left hemihepatectomy (LLH) is commonly used for benign and malignant left liver lesions. We compared the benefits and drawbacks of LLH from the…

Date: 2024-05-24

Application value of MRI-guided wire localization to the non-palpable breast lesions only shown in Breast MRI

Abstract: Introduction: Magnetic resonance imaging (MRI)-guided wire localization can be applied to assist to remove suspected breast lesions accurately. This study aimed to…

Date: 2024-05-24

“It's more than just a conversation about the heart”: exploring barriers, enablers, and opportunities for improving the delivery and uptake of cardiac neurodevelopmental follow-up care

Abstract: Introduction: Surveillance, screening, and evaluation for neurodevelopmental delays is a pivotal component of post-surgical care for children with congenital heart…

Date: 2024-05-24