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Clinical exome sequencing by general pediatricians: high clinical utility and no evidence of inappropriate testing

Abstract: Background: Genetic disorders account for a large percentage of admissions and outpatient visits to children's hospitals around the world. Clinical exome sequencing…

Date: 2024-04-22

How internet healthcare information overflow affects farmers’ healthcare consumption: insights from China

Abstract: Introduction: In the context of the deep coupling and synergistic development of digital villages and healthy villages, the development of China’s rural society harbors…

Date: 2024-04-22

Inflammatory cytokines may mediate the causal relationship between gut microbiota and male infertility: a bidirectional, mediating, multivariate Mendelian randomization study

Abstract: Introduction: Studies have shown that the gut microbiota is associated with male infertility (MI). However, their causal relationship and potential mediators need more…

Date: 2024-04-22

Temporal trends in the prevalence and death of ischemic heart disease in women of childbearing age from 1990 to 2019: a multilevel analysis based on the Global Burden of Disease Study 2019

Abstract: Background: Our objective is to describe the current prevalence and death of ischemic heart disease (IHD) in women of childbearing age (WCBA) at the global, regional,…

Date: 2024-04-22

Relationship between fibroblast growth factor in plasma and carotid plaque neovascularization: a pilot study

Abstract: Background: Unstable atherosclerotic carotid plaques with intraplaque neovascularization (IPN) carry a substantial risk for ischemic stroke. Conventional ultrasound…

Date: 2024-04-22

The causal relationship between sarcoidosis and autoimmune diseases: a bidirectional Mendelian randomization study in FinnGen

Abstract: Background: Sarcoidosis has been considered to be associated with many autoimmune diseases (ADs), but the cause-and-effect relationship between these two diseases has…

Date: 2024-04-22

Higher TIGIT+ ?? TCM cells may predict poor prognosis in younger adult patients with non-acute promyelocytic AML

Abstract: Introduction: ?? T cells recognize and exert cytotoxicity against tumor cells. They are also considered potential immune cells for immunotherapy. Our previous study…

Date: 2024-04-22