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Post-traumatic stress and future substance use outcomes: leveraging antecedent factors to stratify risk

Abstract: Background: Post-traumatic stress disorder (PTSD) and substance use (tobacco, alcohol, and cannabis) are highly comorbid. Many factors affect this relationship,…

Date: 2024-03-27

Prioritizing patients for hip fracture surgery: the role of frailty and cardiac risk

Abstract: Introduction: The number of patients with hip fractures continues to rise as the average age of the population increases. Optimizing outcomes in this cohort is…

Date: 2024-03-27

DNA damage levels in peripheral blood mononuclear cells before and after first cycle of chemotherapy have comparable prognostic values in germ cell tumor patients

Abstract: Background: Germ cell tumors (GCTs) represent the most frequent solid malignancy in young men. This malignancy is highly curable by cisplatin (CDDP)-based chemotherapy.…

Date: 2024-03-27

Revisiting roles of mast cells and neural cells in keloid: exploring their connection to disease activity

Abstract: Background: Mast cells (MCs) and neural cells (NCs) are important in a keloid microenvironment. They might contribute to fibrosis and pain sensation within the keloid.…

Date: 2024-03-27

Comprehensive analysis of fibroblast activation protein expression across 23 tumor indications: insights for biomarker development in cancer immunotherapies

Abstract: Introduction: Fibroblast activation protein (FAP) is predominantly upregulated in various tumor microenvironments and scarcely expressed in normal tissues.

Date: 2024-03-27

Biliary atresia in preterm infants: a single center experience and review of literature

Abstract: Introduction: The diagnosis of biliary atresia (BA) remains challenging, and there is still uncertainty regarding the optimal time to perform a Kasai portoenterostomy…

Date: 2024-03-27

Iron metabolism disorder and multiple sclerosis: a comprehensive analysis

Abstract: Background: Multiple sclerosis (MS) is the most common chronic inflammatory disease of the central nervous system. Currently, the pathological mechanisms of MS are not…

Date: 2024-03-27

Cannabidiol usage, efficacy, and side effects: analyzing the impact of health conditions, medications, and cannabis use in a cross-sectional online pilot study

Abstract: Background: Products containing cannabidiol (CBD) are attracting attention because of their potential therapeutic benefits and positive impacts on well-being and mental…

Date: 2024-03-27

Immunoproteomics enable broad identification of new Aspergillus fumigatus antigens in severe equine asthma

Abstract: Introduction: Severe equine asthma (SEA) is a common chronic disease of adult horses with characteristic recurrent airway obstruction and similarities to neutrophilic…

Date: 2024-03-27