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Implantation of atrial flow regulator devices in patients with congenital heart disease and children with severe pulmonary hypertension or cardiomyopathy—an international multicenter case series

Abstract: Background: The Occlutech Atrial Flow Regulator (AFR) is a self-expandable double-disc nitinol device with a central fenestration. Its use has been approved in the adult…

Date: 2024-01-31

High resolution and contrast 7 tesla MR brain imaging of the neonate

Abstract: Introduction: Ultra-high field MR imaging offers marked gains in signal-to-noise ratio, spatial resolution, and contrast which translate to improved pathological and…

Date: 2024-01-31

Development and deployment of a nationwide predictive model for chronic kidney disease progression in diabetic patients

Abstract: Aim: Chronic kidney disease (CKD) is a major complication of diabetes and a significant disease burden on the healthcare system. The aim of this work was to apply a…

Date: 2024-01-31

Parental perceptions of informed consent in a study of tracheal intubations in neonatal intensive care

Abstract: Background and objective: Obtaining informed consent in neonatal emergency research is challenging. The aim of this study was to assess parental perceptions of informed…

Date: 2024-01-31

The magnitude of correlation between deadlift 1RM and jumping performance is sports dependent

Abstract: Introduction: Based on the assumption of maximal strength as a basic ability, several studies show a high influence of maximum strength on jumping performance in several…

Date: 2024-01-31

Pharmacogenomics of intravenous immunoglobulin response in Kawasaki disease

Abstract: Introduction: Kawasaki disease (KD) is a diffuse vasculitis in children. Response to high dose intravenous gamma globulin (IVIG), the primary treatment, varies according…

Date: 2024-01-31

A novel gene signature related to focal adhesions for distinguishing and predicting the prognosis of lung squamous cell carcinoma

Abstract: Background: Lung squamous cell carcinoma (LUSC) is a devastating and difficult-to-treat type of lung cancer, and the prognosis of LUSC is the worst. The functional roles…

Date: 2024-01-31

Integrating single-cell and bulk transcriptomic analyses to develop a cancer-associated fibroblast-derived biomarker for predicting prognosis and therapeutic response in breast cancer

Abstract: Background: Cancer-associated fibroblasts (CAFs) contribute to the progression and treatment of breast cancer (BRCA); however, risk signatures and molecular targets…

Date: 2024-01-31

Three years of COVID-19 in children that attend the Mexican Social Security Institute's 1,350 child day-care centers, 2020–2023

Abstract: Background: Studies have suggested that children are less likely than adults to develop COVID-19; however, with the emergence of SARS-CoV-2 variants, hospitalization and…

Date: 2024-01-31

Persistent CD8+ T cell proliferation and activation in COVID-19 adult survivors with post-acute sequelae: a longitudinal, observational cohort study of persistent symptoms and T cell markers

Abstract: Introduction: Post-acute sequelae of COVID-19 affects the quality of life of many COVID-19 survivors, yet the etiology of post-acute sequelae of COVID-19 remains…

Date: 2024-01-31