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Correlation between tear cytokine profiles and corneal injury degree in patients with dry eye syndrome

Abstract: Dry eye syndrome (DES) is a very common ocular surface disorder that is closely related to corneal damage. However, the relationship between tear cytokines in patients…

Date: 2026-03-19

Proteomic profiling of spontaneous myopia in guinea pigs

Abstract: There is a subset of guinea pigs born with spontaneous myopia that exhibit fundus characteristics similar to those of high myopia. This study aimed to further identify…

Date: 2026-03-19

Smartphone-based digital phenotyping for characterizing post-operative recovery in patients undergoing surgery for cervical myelopathy

Abstract: This study aimed at investigating the feasibility of using personal smartphones to characterize mobility in patients after surgery for cervical myelopathy. The specific…

Date: 2026-03-19

Multiomics integration of single-cell transcriptomics and bulk sequencing data identifies key biomarkers and predictive models for IBD subtype classification

Abstract: Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn’s disease (CD), represents a diagnostic challenge owing to its overlapping clinical…

Date: 2026-03-19

Italian style coffee consumption and metabolically dysfunctional-associated steatotic liver disease (MASLD): a cohort population study in Southern Italy

Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD) is currently the most prevalent chronic liver disease globally, and its incidence is rising consistently…

Date: 2026-03-19

Visceral to subcutaneous fat area ratio as a novel prognostic biomarker in cirrhosis patients undergoing TIPS: a retrospective study

Abstract: This research aims to explore the predictive value of the visceral-to-subcutaneous fat area ratio (V/S ratio) for post-TIPS overt hepatic encephalopathy (OHE) and…

Date: 2026-03-19

Hidden diagnoses among patients with double seronegative myasthenia gravis

Abstract: Double seronegative myasthenia gravis (dSnMG) is defined as myasthenia gravis (MG) without detectable antibodies to acetylcholine receptor (AChR) and muscle-specific…

Date: 2026-03-19

Gut microbiota 16S rRNA profiling with plasma and urine metabolomics in vestibular migraine

Abstract: Vestibular migraine (VM) pathophysiology remains unclear, with research often extrapolating from migraine (M) studies. The microbiota-gut-brain axis represents a novel…

Date: 2026-03-19

A conserved monocyte activation program links brain injury to systemic immune adaptation and clinical outcomes

Abstract: Systemic immune dysregulation after traumatic brain injury (TBI) contributes to secondary complications and influences long-term recovery, yet the cellular and molecular…

Date: 2026-03-19

Endotoxin tolerance enhances breast cancer aggressiveness and alters inflammatory marker expression in tumor and spleen of mice

Abstract: Endotoxin tolerance (ET) is an immunological state in which repeated exposure to endotoxins such as lipopolysaccharide (LPS) leads to reprogramming of the immune system…

Date: 2026-03-19